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D-Cellobiose (CAS 528-50-7)

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Alternate Names:
4-O-β-D-Glucopyranosyl-D-glucose; D(+)-Cellobiose
Application:
D-Cellobiose is a substrate of β-glucosidase
CAS Number:
528-50-7
Molecular Weight:
342.3
Molecular Formula:
C12H22O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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D-Cellobiose, a disaccharide sugar formed by two glucose molecules connected through a β-1,4 glycosidic bond, presents as a white, crystalline solid and exhibits solubility in water. It assumes a role as a constituent of cellulose, the primary structural component of plant cell walls. In the realm of scientific research, D-Cellobiose finds extensive applications. Although the precise mechanism of action of D-Cellobiose remains incompletely understood, it is hypothesized that cells uptake this sugar through specialized transporter proteins. Subsequently, enzymes break down D-Cellobiose into glucose molecules, which can then be utilized for energy production or other metabolic activities.


D-Cellobiose (CAS 528-50-7) References

  1. Determination of neutral carbohydrates by CZE with direct UV detection.  |  Rovio, S., et al. 2007. Electrophoresis. 28: 3129-35. PMID: 17661315
  2. Impact of pretreated Switchgrass and biomass carbohydrates on Clostridium thermocellum ATCC 27405 cellulosome composition: a quantitative proteomic analysis.  |  Raman, B., et al. 2009. PLoS One. 4: e5271. PMID: 19384422
  3. The last piece in the cellulase puzzle: the characterisation of beta-glucosidase from the herbivorous gecarcinid land crab Gecarcoidea natalis.  |  Allardyce, BJ., et al. 2010. J Exp Biol. 213: 2950-7. PMID: 20709923
  4. Cultured representatives of two major phylogroups of human colonic Faecalibacterium prausnitzii can utilize pectin, uronic acids, and host-derived substrates for growth.  |  Lopez-Siles, M., et al. 2012. Appl Environ Microbiol. 78: 420-8. PMID: 22101049
  5. Lignocellulolytic enzymes and bacteria associated with the digestive tracts of Stenochironomus (Diptera: Chironomidae) larvae.  |  Koroiva, R., et al. 2013. Genet Mol Res. 12: 3421-34. PMID: 23613276
  6. Fast carbohydrate analysis via liquid chromatography coupled with ultra violet and electrospray ionization ion trap detection in 96-well format.  |  Rühmann, B., et al. 2014. J Chromatogr A. 1350: 44-50. PMID: 24861788
  7. Growth and host interaction of mouse segmented filamentous bacteria in vitro.  |  Schnupf, P., et al. 2015. Nature. 520: 99-103. PMID: 25600271
  8. Development of a plasmid-based expression system in Clostridium thermocellum and its use to screen heterologous expression of bifunctional alcohol dehydrogenases (adhEs).  |  Hon, S., et al. 2016. Metab Eng Commun. 3: 120-129. PMID: 29142822
  9. Deactivation and Regeneration of Sulfonated Carbon Catalysts in Hydrothermal Reaction Environments.  |  Scholz, D., et al. 2018. ChemSusChem. 11: 2189-2201. PMID: 29733550
  10. Carbon sources and XlnR-dependent transcriptional landscape of CAZymes in the industrial fungus Talaromyces versatilis: when exception seems to be the rule.  |  Llanos, A., et al. 2019. Microb Cell Fact. 18: 14. PMID: 30691469
  11. Characterization of the cellulase-secretome produced by the Antarctic bacterium Flavobacterium sp. AUG42.  |  Herrera, LM., et al. 2019. Microbiol Res. 223-225: 13-21. PMID: 31178046
  12. Calcium channel CNGC19 mediates basal defense signaling to regulate colonization by Piriformospora indica in Arabidopsis roots.  |  Jogawat, A., et al. 2020. J Exp Bot. 71: 2752-2768. PMID: 31957790
  13. Co-incidence of Damage and Microbial Patterns Controls Localized Immune Responses in Roots.  |  Zhou, F., et al. 2020. Cell. 180: 440-453.e18. PMID: 32032516
  14. Hydrophobic functional liquids based on trioctylphosphine oxide (TOPO) and carboxylic acids.  |  Byrne, EL., et al. 2020. Phys Chem Chem Phys. 22: 24744-24763. PMID: 33107499
  15. Conjugation Protocol Optimised for Roseburia inulinivorans and Eubacterium rectale.  |  Sheridan, PO., et al. 2020. Bio Protoc. 10: e3575. PMID: 33659545
  16. Selective Isolation of Bifidobacterium From Human Faeces Using Pangenomics, Metagenomics, and Enzymology.  |  Yang, S., et al. 2021. Front Microbiol. 12: 649698. PMID: 33967985
  17. RNase1 can modulate gut microbiota and metabolome after Aeromonas hydrophila infection in blunt snout bream.  |  Geng, R., et al. 2021. Environ Microbiol. 23: 5258-5272. PMID: 33973327

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D-Cellobiose, 5 g

sc-280654
5 g
$45.00

D-Cellobiose, 25 g

sc-280654A
25 g
$110.00

difference between D-cellobiose and D-(+)-cellobiose

Asked by: Nneka
Thank you for your question. The positive and - refer to what direction the polarized light is rotated: (-) is left and (+) is right. This product is +. Please contact our Technical Service Department by phone, e-mail or live chat if you have any further questions.
Answered by: Tech Service
Date published: 2017-08-28
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Rated 5 out of 5 by from Lawley et alLawley et al. (PubMed ID 23851085) found that Lactobacillus ruminis was able to use D-cellobiose (CDP4) present in beta-glucan hydrolysates to increase transcription in the early growth phase. -SCBT Publication Review
Date published: 2015-07-06
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D-Cellobiose is rated 5.0 out of 5 by 1.
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