Molecular structure of D-Carnitine, CAS Number: 541-14-0
D-Carnitine (CAS 541-14-0)
CAS Number:
541-14-0
Purity:
≥96%
Molecular Weight:
161.20
Molecular Formula:
C7H15NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
D-Carnitine is used as a building block for antidiabetic, microbicidal compounds. It′s an amino acid derivative and has significant biochemical and physiological effects that make it useful for scientific research. Its involvement in key biochemical processes, including energy metabolism, fatty acid oxidation, and muscle contraction, has been widely studied. As an acyl carrier, D-Carnitine facilitates the transfer of acyl groups from coenzyme A to carnitine and ultimately to the mitochondria. This process is for the oxidation of fatty acids, which in turn is necessary for the production of ATP, the energy currency of the cell.
D-Carnitine (CAS 541-14-0) References
- Enantiomeric separation of D- and L-carnitine by integrating on-line derivatization with capillary zone electrophoresis. | Mardones, C., et al. 1999. J Chromatogr A. 849: 609-16. PMID: 10457455
- Acylcarnitine analogues as topical, microbicidal spermicides. | Savle, PS., et al. 1999. Bioorg Med Chem Lett. 9: 2545-8. PMID: 10498205
- Enzymatic cycling assay for D-carnitine determination. | Obón, JM., et al. 1999. Anal Biochem. 274: 34-9. PMID: 10527494
- A chiral HPLC method for the determination of low amounts of D-carnitine in L-carnitine after derivatization with (+)-FLEC. | Freimüller, S. and Altorfer, H. 2002. J Pharm Biomed Anal. 30: 209-218. PMID: 12191705
- Carnitine deficiency: a possible risk factor in paracetamol hepatotoxicity. | Arafa, HM. 2009. Arch Toxicol. 83: 139-50. PMID: 18597074
- Sensitive determination of D-carnitine as enantiomeric impurity of levo-carnitine in pharmaceutical formulations by capillary electrophoresis-tandem mass spectrometry. | Sánchez-Hernández, L., et al. 2010. J Pharm Biomed Anal. 53: 1217-23. PMID: 20392588
- Functional differences between l- and d-carnitine in metabolic regulation evaluated using a low-carnitine Nile tilapia model. | Li, JM., et al. 2019. Br J Nutr. 122: 625-638. PMID: 32124711
- Chiral molecular imprinted sensor for highly selective determination of D-carnitine in enantiomers via dsDNA-assisted conformation immobilization. | Zhang, L., et al. 2020. Anal Chim Acta. 1136: 82-90. PMID: 33081952
- Carnitine is a pharmacological allosteric chaperone of the human lysosomal α-glucosidase. | Iacono, R., et al. 2021. J Enzyme Inhib Med Chem. 36: 2068-2079. PMID: 34565280
- Uptake of L-carnitine, D-carnitine and acetyl-L-carnitine by isolated guinea-pig enterocytes. | Gross, CJ., et al. 1986. Biochim Biophys Acta. 886: 425-33. PMID: 3708005
- Comparison of the effects of L-carnitine, D-carnitine and acetyl-L-carnitine on the neurotoxicity of ammonia. | Matsuoka, M. and Igisu, H. 1993. Biochem Pharmacol. 46: 159-64. PMID: 8347126
- Purification and characterization of D(+)-carnitine dehydrogenase from Agrobacterium sp.--a new enzyme of carnitine metabolism. | Hanschmann, H. and Kleber, HP. 1997. Biochim Biophys Acta. 1337: 133-42. PMID: 9003445
- Biotransformation of D(+)-carnitine into L(-)-carnitine by resting cells of Escherichia coli O44 K74. | Castellar, MR., et al. 1998. J Appl Microbiol. 85: 883-90. PMID: 9830124
Activator of:
CDV.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
D-Carnitine, 1 g | sc-358752 | 1 g | $383.00 |