Date published: 2025-10-2

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D-Asparagine (CAS 2058-58-4)

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Alternate Names:
(R)-2-Aminosuccinamic acid (R)-2-Aminosuccinic acid 4-amide D-Aspartic acid 4-amide
CAS Number:
2058-58-4
Purity:
≥99%
Molecular Weight:
132.12
Molecular Formula:
C4H8N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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D-Asparagine is an amino acid that belongs to the asparagine family. It is the D enantiomer of asparagine, meaning it has a specific spatial arrangement of atoms. D-Asparagine is a non-proteinogenic amino acid, which means it is not found in proteins. It can be synthesized in the laboratory or derived from natural sources. D-Asparagine is known for its potential biological activities and is involved in various physiological processes, including neurotransmission and cell signaling. It has also been studied for its potential role in neuroprotection and as a therapeutic target for certain neurological disorders.


D-Asparagine (CAS 2058-58-4) References

  1. pH and kinetic isotope effects in d-amino acid oxidase catalysis.  |  Harris, CM., et al. 2001. Eur J Biochem. 268: 5504-20. PMID: 11683874
  2. Biosensor for asparagine using a thermostable recombinant asparaginase from Archaeoglobus fulgidus.  |  Li, J., et al. 2002. Anal Chem. 74: 3336-41. PMID: 12139037
  3. Inhibition of L-asparaginase in extracts of Mycobacterium phlei by D-asparagine.  |  GROSSOWICZ, N. and HALPERN, YS. 1956. Nature. 177: 623-4. PMID: 13321923
  4. Identification of an essential gene responsible for D-Asp incorporation in the Lactococcus lactis peptidoglycan crossbridge.  |  Veiga, P., et al. 2006. Mol Microbiol. 62: 1713-24. PMID: 17083466
  5. The discovery of stereoselectivity at biological receptors: Arnaldo Piutti and the taste of the asparagine enantiomers--history and analysis on the 125th anniversary.  |  Gal, J. 2012. Chirality. 24: 959-76. PMID: 23034823
  6. Using D-Amino Acids to Delineate the Mechanism of Protein Folding: Application to Trp-cage.  |  Culik, RM., et al. 2013. Chem Phys. 422: PMID: 24307748
  7. Substrate specificity of duckling hepatic and renal D-amino acid oxidase.  |  Elkin, RG. and Lyons, ML. 1988. Poult Sci. 67: 851-4. PMID: 2900508
  8. Plasma d-amino acids are associated with markers of immune activation and organ dysfunction in people with HIV.  |  Yap, SH., et al. 2022. AIDS. 36: 911-921. PMID: 35212669
  9. Chiral resolution of plasma amino acids reveals enantiomer-selective associations with organ functions.  |  Suzuki, M., et al. 2022. Amino Acids. 54: 421-432. PMID: 35226151
  10. Depletion of d- and l-asparagine in cerebrospinal fluid in acute lymphoblastic leukemia during PEGasparaginase therapy.  |  Brigitha, LJ., et al. 2022. Pediatr Blood Cancer. 69: e29865. PMID: 35880973
  11. Activation of d-Asparagine and d-Glutamine Derivatives Using the Mitsunobu Reaction.  |  Fu, X., et al. 2023. Org Lett. 25: 1310-1314. PMID: 36800493
  12. Modified ammonia electrode method to investigate D-asparagine breakdown by Campylobacter strains.  |  Karmali, MA., et al. 1986. J Clin Microbiol. 23: 743-7. PMID: 3700627
  13. Utilization of D-asparagine by Saccharomyces cerevisiae.  |  Dunlop, PC., et al. 1976. J Bacteriol. 125: 999-1004. PMID: 767332

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D-Asparagine, 25 g

sc-255052
25 g
$339.00