Molecular structure of D-64131, CAS Number: 74588-78-6
D-64131 (CAS 74588-78-6)
Alternate Names:
(5-Methoxy-1H-indol-2-yl)phenylmethanone
Application:
D-64131 is a novel inhibitor of Tubulin polymerization
CAS Number:
74588-78-6
Purity:
≥99%
Molecular Weight:
251.28
Molecular Formula:
C16H13NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
D-64131 is a novel inhibitor of tubulin polymerization that competitively binds with [(3)H]colchicine to αβ-tubulin. D-64131 is cytotoxic and inhibits tumor cell proliferation in vitro (IC50 = 74 nM).
D-64131 (CAS 74588-78-6) References
Mahboobi et al (2001) Synthetic 2-aroylindole derivatives as a new class of potent tubulin-inhibitory, antimitotic agents. J.Med.Chem. 44 4535. Beckers et al (2002) 2-aroylindoles, a novel class of potent, orally active small molecule tubulin inhibitors. Cancer Res. 62 3113.Inhibitor of:
Tubulin.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
D-64131, 10 mg | sc-203908 | 10 mg | $165.00 | |||
D-64131, 50 mg | sc-203908A | 50 mg | $700.00 |