D(−)-2-Amino-4-phosphonobutanoic acid (D-AP4) (CAS 78739-01-2)
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D(−)-2-Amino-4-phosphonobutanoic acid, often referred to as D-AP4, is a compound that plays a significant role in neuroscience research. It acts as a selective agonist for group III metabotropic glutamate receptors (mGluRs), which are G protein-coupled receptors involved in modulating neurotransmission in the central nervous system. In electrophysiological studies, D(−)-2-Amino-4-phosphonobutanoic acid (D-AP4) is used to probe the function of these receptors in synaptic transmission and to understand their role in neurophysiological processes. Additionally, D(−)-2-Amino-4-phosphonobutanoic acid (D-AP4) is employed in neuropharmacology to dissect the pathways and mechanisms by which group III mGluRs affect neuronal excitability and plasticity. The compound′s ability to mimic the action of certain neurotransmitters also makes it useful in exploring the downstream effects of mGluR activation, including changes in second messenger systems.
D(−)-2-Amino-4-phosphonobutanoic acid (D-AP4) (CAS 78739-01-2) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
D(−)-2-Amino-4-phosphonobutanoic acid (D-AP4), 2.5 mg | sc-200429 | 2.5 mg | $428.00 |