Molecular structure of Cytosine, CAS Number: 71-30-7
Cytosine (CAS 71-30-7)
Alternate Names:
4-Amino-2-hydroxypyrimidine; 4-Aminopyrimidin-2-(1H)-one
Application:
Cytosine is a nucleoside for proteomics research
CAS Number:
71-30-7
Purity:
≥98%
Molecular Weight:
111.10
Molecular Formula:
C4H5N3O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Cytosine is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). Cytosine reagent is used in a wide variety of research applications, as an enzyme substrate or precursor of effector molecules such as cytosine sugars. Cytosine serves as useful in the examination of protein, enzyme, and other molecule structure and function.
Cytosine (CAS 71-30-7) References
- Principal causes of hot spots for cytosine to thymine mutations at sites of cytosine methylation in growing cells. A model, its experimental support and implications. | Lutsenko, E. and Bhagwat, AS. 1999. Mutat Res. 437: 11-20. PMID: 10425387
- Cytosine methylation and DNA repair. | Walsh, CP. and Xu, GL. 2006. Curr Top Microbiol Immunol. 301: 283-315. PMID: 16570853
- Spontaneous deamination of cytosine and 5-methylcytosine residues in DNA and replacement of 5-methylcytosine residues with cytosine residues. | Ehrlich, M., et al. 1990. Mutat Res. 238: 277-86. PMID: 2188124
- Cytosine derivatives form hemiprotonated dimers in solution and the gas phase. | Moehlig, AR., et al. 2012. Org Lett. 14: 2560-3. PMID: 22571841
- New cytosine derivatives as inhibitors of DNA methylation. | Plitta, B., et al. 2012. Eur J Med Chem. 55: 243-54. PMID: 22854677
- Cytosine unstacking and strand slippage at an insertion-deletion mutation sequence in an overhang-containing DNA duplex. | Manjari, SR., et al. 2014. Biochemistry. 53: 3807-16. PMID: 24854722
- Expanding the epigenetic landscape: novel modifications of cytosine in genomic DNA. | Kriaucionis, S. and Tahiliani, M. 2014. Cold Spring Harb Perspect Biol. 6: a018630. PMID: 25274704
- Cytosine DNA methylation at promoter of non LTR retrotransposon and heat shock protein gene (HSP70) of Entamoeba histolytica and lack of correlation with transcription status. | Agrahari, M., et al. 2017. Mol Biochem Parasitol. 212: 21-27. PMID: 28082182
- Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging. | Oh, G., et al. 2018. Nat Commun. 9: 644. PMID: 29440637
- Cytosine Methylation Affects the Mutability of Neighboring Nucleotides in Germline and Soma. | Kusmartsev, V., et al. 2020. Genetics. 214: 809-823. PMID: 32079595
- Antigen Retrieval for Immunostaining of Modified Cytosine Species. | Celik-Uzuner, S. 2021. Methods Mol Biol. 2198: 217-226. PMID: 32822035
- Modified cytosines versus cytosine in a DNA polymerase: retrieving thermodynamic and kinetic constants at the single molecule level. | Lee, JY. and Park, JW. 2022. Analyst. 147: 341-348. PMID: 34935781
- Global analysis of cytosine and adenine DNA modifications across the tree of life. | Varma, SJ., et al. 2022. Elife. 11: PMID: 35900202
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cytosine, 5 g | sc-211162 | 5 g | $38.00 | |||
Cytosine, 25 g | sc-211162A | 25 g | $45.00 | |||
Cytosine, 100 g | sc-211162B | 100 g | $131.00 |