Cytokeratin 18 Antibody (DA-7): sc-51583
- Cytokeratin 18 Antibody (DA-7) is a mouse monoclonal IgG1, cited in 5 publications, provided at 100 µg/ml
- raised against human breast carcinoma cell line PMC-42
- recommended for detection of Cytokeratin 18 of human origin by WB, IP, IF and IHC(P)
- See Cytokeratin 18 (RGE53): sc-32329 for Cytokeratin 18 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Cytokeratin 18 Antibody (DA-7). This work is in progress.
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SEE ALSO...
Cytokeratin 18 Antibody (DA-7) is a mouse monoclonal IgG1 antibody that detects Cytokeratin 18 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Cytokeratin 18 is a vital component of the cytoskeleton in epithelial cells, contributing significantly to structural integrity and resilience. Anti-Cytokeratin 18 antibody (DA-7) recognizes a protein predominantly located in the cytoplasm, where Cytokeratin 18 forms a network of intermediate filaments providing mechanical support and shape to cells. Proper localization of Cytokeratin 18 is crucial for maintaining epithelial tissue architecture, and disruption can lead to various pathological conditions, including cancer. Cytokeratin 18 monoclonal antibody (DA-7) helps detect this important biomarker for epithelial-derived tumors, as expression levels can indicate differentiation status of malignant cells. Cytokeratin 18 undergoes post-translational modifications, including phosphorylation, which influences interactions with other proteins and overall cellular function. Cytokeratin 18 (DA-7) antibody serves as an essential tool for researchers studying epithelial biology and cancer pathology, enabling exploration of Cytokeratin 18′s role in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cytokeratin 18 Antibody (DA-7) | sc-51583 | 100 µg/ml | $316.00 |