Cytidine (CAS 65-46-3)
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Cytidine is a constituent of nucleic acids originally isolated in yeast. Cytidine, a pyrimidine nucleoside, serves as an indispensable component within the genetic framework of both RNA and DNA. Its origins lie as a derivative of uracil, and it exists universally among all living organisms. In the intricate realm of cellular processes, cytidine plays a vital role, functioning as a fundamental building block of the genetic code. Moreover, it actively contributes to essential tasks like cell growth, differentiation, and the synthesis of proteins and other essential molecules. While the complete mechanism of cytidine′s action remains somewhat elusive, it is believed to have a significant influence on protein synthesis and DNA replication regulation. This is thought to occur through interactions with specific proteins, including transcription factors and DNA polymerases, which in turn modulate gene expression and DNA replication. Furthermore, cytidine is believed to play a part in the generation of new RNA molecules and the repair of damaged DNA. As a precursor for the synthesis of molecules like uridine and cytidine triphosphate, cytidine′s involvement extends to the production of energy, adding yet another layer to its importance in the biological realm.
Cytidine (CAS 65-46-3) References
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- Comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry analysis of metabolites in fermenting and respiring yeast cells. | Mohler, RE., et al. 2006. Anal Chem. 78: 2700-9. PMID: 16615782
- Cytidine is a novel substrate for wild-type concentrative nucleoside transporter 2. | Nagai, K., et al. 2006. Biochem Biophys Res Commun. 347: 439-43. PMID: 16828706
- Collision-induced dissociation of cytidine and its derivatives. | Jensen, SS., et al. 2007. J Mass Spectrom. 42: 49-57. PMID: 17149798
- Cytidine-directed rapid synthesis of water-soluble and highly yellow fluorescent bimetallic AuAg nanoclusters. | Zhang, Y., et al. 2014. Langmuir. 30: 10910-7. PMID: 25158043
- Practical synthesis of cytidine-5-carboxamide-modified nucleotide reagents. | Rohloff, JC., et al. 2015. Nucleosides Nucleotides Nucleic Acids. 34: 180-98. PMID: 25710355
- Surface enhanced Raman detection of the colon cancer biomarker cytidine by using magnetized nanoparticles of the type Fe3O4/Au/Ag. | Xiang, Y., et al. 2018. Mikrochim Acta. 185: 195. PMID: 29594694
- Photochemical conversion of a cytidine derivative to a thymidine analog via [2+2]-cycloaddition. | Li, X., et al. 2018. Photochem Photobiol Sci. 17: 1049-1055. PMID: 29926889
- Cytidine- and guanosine-based nucleotide-lipids. | Alies, B., et al. 2018. Org Biomol Chem. 16: 4888-4894. PMID: 29932190
- Acetylation of Cytidine in mRNA Promotes Translation Efficiency. | Arango, D., et al. 2018. Cell. 175: 1872-1886.e24. PMID: 30449621
- Cytidine deaminase enables Toll-like receptor 8 activation by cytidine or its analogs. | Furusho, K., et al. 2019. Int Immunol. 31: 167-173. PMID: 30535046
- Determination of cytidine modifications in human urine by liquid chromatography - Mass spectrometry analysis. | Zhang, YF., et al. 2019. Anal Chim Acta. 1081: 103-111. PMID: 31446947
- A concise route to MK-4482 (EIDD-2801) from cytidine. | Vasudevan, N., et al. 2020. Chem Commun (Camb). 56: 13363-13364. PMID: 33030468
- Cytidine deaminases catalyze the conversion of N(S,O)4-substituted pyrimidine nucleosides. | Urbelienė, N., et al. 2023. Sci Adv. 9: eade4361. PMID: 36735785
- Cytidine Alleviates Dyslipidemia and Modulates the Gut Microbiota Composition in ob/ob Mice. | Niu, K., et al. 2023. Nutrients. 15: PMID: 36904146
- A simplified procedure for a rapid and reliable assay of both glycogen and trehalose in whole yeast cells. | Parrou, JL. and François, J. 1997. Anal Biochem. 248: 186-8. PMID: 9177741
- Effect of diet on the urinary excretion of hippuric acid and other dietary-derived aromatics in rat. A complex interaction between diet, gut microflora and substrate specificity. | Phipps, AN., et al. 1998. Xenobiotica. 28: 527-37. PMID: 9622854
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cytidine, 1 g | sc-221450 | 1 g | $42.00 |