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Cytidine-5′-monophosphate disodium salt (CAS 6757-06-8)

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Alternate Names:
5′-CMP.2Na
CAS Number:
6757-06-8
Purity:
≥99%
Molecular Weight:
367.16
Molecular Formula:
C9H12N3Na2O8P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cytidine-5′-monophosphate disodium salt (CMP) stands as a nucleotide present, playing a role in the synthesis of DNA and RNA. The applications of Cytidine-5′-monophosphate disodium salt in scientific applications are manifold. It serves as a means to unravel cellular processes, including DNA replication, transcription, and translation, and sheds light on enzyme activities. It is instrumental in gene expression studies, actively participating in the regulatory mechanisms governing gene expression. It undergoes conversion to deoxycytidine monophosphate (dCMP), which subsequently transforms into deoxyribonucleotides that integrate into elongating DNA strands. As for RNA synthesis, Cytidine-5′-monophosphate disodium salt is converted into uridine monophosphate (UMP), which subsequently gives rise to ribonucleotides that are incorporated into developing RNA strands.


Cytidine-5′-monophosphate disodium salt (CAS 6757-06-8) References

  1. Charge transfer complexes of adenosine-5'-monophosphate and cytidine-5'-monophosphate with water-soluble cobalt(II) Schiff base complexes in aqueous solution.  |  Boghaei, DM. and Gharagozlou, M. 2006. Spectrochim Acta A Mol Biomol Spectrosc. 63: 139-48. PMID: 15950536
  2. Analysis of nucleosides and monophosphate nucleotides from mushrooms with reversed-phase HPLC.  |  Ranogajec, A., et al. 2010. J Sep Sci. 33: 1024-33. PMID: 20175083
  3. Counter-current chromatographic separation of nucleic acid constituents with a hydrophilic solvent system.  |  Shibusawa, Y., et al. 2010. J Chromatogr A. 1217: 3457-60. PMID: 20362294
  4. The Full Cytosine-Cytosine Base Paring: Self-Assembly and Crystal Structure.  |  Li, Z., et al. 2023. Chemistry. 29: e202203979. PMID: 36757279
  5. New retention mechanism of mononucleotides with buffer concentrations in ion-suppressing RP-HPLC  |  Lee, J. W., & Row, K. H. 2001. Biotechnology and Bioprocess Engineering. 6: 37-41.
  6. The analysis of 5′-mononucleotides in infant formulae by HPLC  |  Perrin, C., Meyer, L., Mujahid, C., & Blake, C. J. 2001. Food Chemistry. 74(2): 245-253.
  7. THz transmittance measurements of nucleobases and related molecules in the 0.4-to 5.8-THz region using a GaP THz wave generator  |  Nishizawa, J. I., Sasaki, T., Suto, K., Tanabe, T., Saito, K., Yamada, T., & Kimura, T. 2005. Optics Communications. 246(1-3): 229-239.
  8. Dietary supplementation of a purified nucleotide mixture transiently enhanced growth and feed utilization of juvenile red drum, Sciaenops ocellatus  |  Li, P., Gatlin III, D. M., & Neill, W. H. 2007. Journal of the World Aquaculture Society. 38(2): 281-286.
  9. Synthesis, nucleic acid binding and cytotoxicity of oligonuclear ruthenium complexes containing labile ligands  |  Mulyana, Y., Collins, G., & Keene, R. 2011. Journal of Inclusion Phenomena and Macrocyclic Chemistry. 71: 371-379.
  10. Experimental Determination of Metastable Zone Width, Induction Period, and Primary Nucleation Kinetics of Cytidine 5′-Monophosphate Disodium Salt in an Ethanol–Aqueous Mixture  |  Yu, J., Li, A., Chen, X., Chen, Y., Xie, J., Wu, J., & Ying, H. 2013. Journal of Chemical & Engineering Data. 58(5): 1244-1248.
  11. Ca 2+ metal ion adducts with cytosine, cytidine and cytidine 5′-monophosphate: a comprehensive study of calcium reactivity towards building units of nucleic acids  |  Marino, N., Armentano, D., Zanchini, C., & De Munno, G. 2014. CrystEngComm. 16(35): 8286-8296.
  12. Surface-enhanced Raman scattering enhancement factors for RNA mononucleotides on silver nanoparticles  |  Miljanić, S., Ratkaj, M., Avdejev, I., Meglić, K., & Kenđel, A. 2015. Croatica Chemica Acta. 88(4): 387-396.
  13. Supramolecular self-assembly of cytidine monophosphate-di-copper building blocks  |  Mastropietro, T. F., & De Munno, G. 2022. Journal of Coordination Chemistry. 75(11-14): 1886-1898.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cytidine-5′-monophosphate disodium salt, 1 g

sc-500950
1 g
$31.00

Cytidine-5′-monophosphate disodium salt, 5 g

sc-500950A
5 g
$92.00