Molecular structure of Cytidine-5′-diphosphate, CAS Number: 63-38-7
Cytidine-5′-diphosphate (CAS 63-38-7)
Alternate Names:
5′-CDP
CAS Number:
63-38-7
Purity:
98%
Molecular Weight:
403.18
Molecular Formula:
C9H15N3O11P2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Cytidine-5′-diphosphate (CDP) is a nucleotide molecule that consists of a cytidine base attached to a ribose sugar, which in turn is linked to two phosphate groups. It is an essential component in the synthesis of nucleic acids, such as DNA and RNA. Cytidine-5′-diphosphate serves as a building block for the incorporation of cytidine into nucleic acids during DNA and RNA replication and transcription. Cytidine-5′-diphosphate (CDP) is involved in the biosynthesis of phospholipids and glycolipids, and plays a role in cellular signaling and energy transfer processes.
Cytidine-5′-diphosphate (CAS 63-38-7) References
- High-field EPR detection of a disulfide radical anion in the reduction of cytidine 5'-diphosphate by the E441Q R1 mutant of Escherichia coli ribonucleotide reductase. | Lawrence, CC., et al. 1999. Proc Natl Acad Sci U S A. 96: 8979-84. PMID: 10430881
- Studies on mammalian ribonucleotide reductase inhibition by pyridoxal phosphate and the dialdehyde derivatives of adenosine, adenosine 5'-monophosphate, and adenosine 5'-triphosphate. | Cory, JG. and Mansell, MM. 1975. Cancer Res. 35: 390-6. PMID: 1109803
- Structure of 2C-methyl-D-erythritol 2,4- cyclodiphosphate synthase: an essential enzyme for isoprenoid biosynthesis and target for antimicrobial drug development. | Kemp, LE., et al. 2002. Proc Natl Acad Sci U S A. 99: 6591-6. PMID: 11997478
- Interaction centres of pyrimidine nucleotides: cytidine-5'-diphosphate (CDP) and cytidine-5'-triphosphate (CTP) in their reactions with tetramines and Cu(II) ions. | Gasowska, A. 2005. J Inorg Biochem. 99: 1698-707. PMID: 15993946
- Comparison of the cytidine 5'-diphosphate and adenosine 5'-diphosphate reductase activities of mammalian ribonucleotide reductase. | Cory, JG. and Mansell, MM. 1975. Cancer Res. 35: 2327-31. PMID: 167952
- The effects of pyrimidine and purine nucleotides on sialyltransferase activity in bovine neurosensory retina. | Unoki, K., et al. 1990. Jpn J Ophthalmol. 34: 409-13. PMID: 2082061
- ENDOR spectroscopy and DFT calculations: evidence for the hydrogen-bond network within α2 in the PCET of E. coli ribonucleotide reductase. | Argirević, T., et al. 2012. J Am Chem Soc. 134: 17661-70. PMID: 23072506
- Pharmacometabolomic approach to predict QT prolongation in guinea pigs. | Park, J., et al. 2013. PLoS One. 8: e60556. PMID: 23593245
- Gemcitabine and carboplatin demonstrate synergistic cytotoxicity in cervical cancer cells by inhibiting DNA synthesis and increasing cell apoptosis. | Jin, G., et al. 2013. Onco Targets Ther. 6: 1707-17. PMID: 24348048
- Variant Bacterial Riboswitches Associated with Nucleotide Hydrolase Genes Sense Nucleoside Diphosphates. | Sherlock, ME., et al. 2019. Biochemistry. 58: 401-410. PMID: 30081631
- Enzymic ribonucleoside reduction at the non-phosphorylated level in Acetabularia. | de Groot, EJ. and Schweiger, HG. 1985. J Cell Sci. 73: 7-18. PMID: 3894391
- Substrate specificity of human ribonucleotide reductase from Molt-4F cells. | Chang, CH. and Cheng, YC. 1979. Cancer Res. 39: 5081-6. PMID: 498135
- Activation of phosphoenolpyruvate-dependent protein kinase by cytidine 5'-triphosphate in rat skeletal muscle. | Mattoo, RL., et al. 1984. FEBS Lett. 165: 117-20. PMID: 6692909
- Inhibition of glycogenin-catalyzed glucosyl and xylosyl transfer by cytidine 5'-diphosphate and related compounds. | Manzella, S., et al. 1995. Arch Biochem Biophys. 320: 361-8. PMID: 7625844
- Cloning and characterization of the R1 and R2 subunits of ribonucleotide reductase from Trypanosoma brucei. | Hofer, A., et al. 1997. Proc Natl Acad Sci U S A. 94: 6959-64. PMID: 9192674
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cytidine-5′-diphosphate, 100 mg | sc-353193 | 100 mg | $297.00 |