Cysteamine (CAS 60-23-1)
See product citations (1)
QUICK LINKS
Cysteamine is a sulfur-containing compound that plays a pivotal role in various biochemical pathways, particularly in the synthesis of coenzyme A, a critical molecule in numerous enzymatic processes. Its mechanism of action revolves around its ability to participate in redox reactions, acting as a powerful reducing agent. This property is for its involvement in the metabolism of amino acids and the detoxification of harmful substances within cells. In research applications, cysteamine has been extensively studied for its ability to modulate levels of glutathione, an essential antioxidant that protects cells from oxidative stress. This modulation is of interest in the exploration of mechanisms to mitigate oxidative damage and maintain cellular homeostasis. Furthermore, cysteamine′s ability to influence cystine levels in lysosomes has made it a subject of study in investigations into the cellular and molecular bases of certain cellular dysfunctions, highlighting its importance in advancing understanding of cellular processes and potential therapeutic targets.
Cysteamine (CAS 60-23-1) References
- Mechanisms for the cytotoxicity of cysteamine. | Jeitner, TM. and Lawrence, DA. 2001. Toxicol Sci. 63: 57-64. PMID: 11509744
- Cysteamine Enhances Biofilm Eradication Efficacy of Calcium Hydroxide. | Guo, W., et al. 2016. J Endod. 42: 742-6. PMID: 26951960
- Metabolic interactions between cysteamine and epigallocatechin gallate. | Izzo, V., et al. 2017. Cell Cycle. 16: 271-279. PMID: 28059601
- Cysteamine-mediated clearance of antibiotic-resistant pathogens in human cystic fibrosis macrophages. | Shrestha, CL., et al. 2017. PLoS One. 12: e0186169. PMID: 28982193
- Cysteamine Protects Neurons from Mutant Huntingtin Toxicity. | Arbez, N., et al. 2019. J Huntingtons Dis. 8: 129-143. PMID: 30856117
- Cysteamine assay for the evaluation of bioactive electrophiles. | Novák, D., et al. 2021. Free Radic Biol Med. 164: 381-389. PMID: 33429019
- Lab-on-a-disc for ultrafast plasmonic assay of cysteamine. | Karmacharya, M., et al. 2021. Biosens Bioelectron. 194: 113584. PMID: 34474276
- Cysteamine Decreases Low-Density Lipoprotein Oxidation, Causes Regression of Atherosclerosis, and Improves Liver and Muscle Function in Low-Density Lipoprotein Receptor-Deficient Mice. | Ahmad, F., et al. 2021. J Am Heart Assoc. 10: e017524. PMID: 34493066
- Cysteamine mitigates torsion/detorsion-induced reperfusion injury via inhibition of apoptosis, oxidative stress and inflammatory responses in experimental rat model. | Afolabi, O., et al. 2022. Andrologia. 54: e14243. PMID: 34498746
- Response to Cysteamine in Osteoclasts Obtained from Patients with Nephropathic Cystinosis: A Genotype/Phenotype Correlation. | Quinaux, T., et al. 2021. Cells. 10: PMID: 34572146
- Cysteamine enhances quality and fertility potential of rooster semen in cooled storage. | Masoudi, R., et al. 2022. Theriogenology. 177: 29-33. PMID: 34656834
- Ocular biodistribution of cysteamine delivered by a sustained release microsphere/thermoresponsive gel eyedrop. | Jimenez, J., et al. 2022. Int J Pharm. 624: 121992. PMID: 35809831
- Examination of the Utility of Cysteamine in the Treatment of Melasma: Current Perspectives. | Sherban, A., et al. 2022. Skinmed. 20: 350-352. PMID: 36314698
- Cysteamine Attenuate Intestinal Reperfusion Injury Induced by Occlusion of Mesenteric Artery by Enhancing Intracellular Thiol Activities. | Alabi, B., et al. 2023. Drug Res (Stuttg). 73: 137-145. PMID: 36574776
- Cysteamine/Cystamine Exert Anti-Mycobacterium abscessus Activity Alone or in Combination with Amikacin. | Palucci, I., et al. 2023. Int J Mol Sci. 24: PMID: 36674717
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cysteamine, 5 g | sc-217991 | 5 g | $87.00 | |||
Cysteamine, 25 g | sc-217991A | 25 g | $233.00 | |||
Cysteamine, 50 g | sc-217991B | 50 g | $433.00 |