Molecular structure of Cyproterone Acetate, CAS Number: 427-51-0
Cyproterone Acetate (CAS 427-51-0)
See product citations (5)
Alternate Names:
Androcur
Application:
Cyproterone Acetate is a compound that induces apoptosis in hepatocytes
CAS Number:
427-51-0
Purity:
≥98%
Molecular Weight:
416.94
Molecular Formula:
C24H29ClO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Cyproterone acetate has antagonistic properties towards the androgen receptor (IC50 = 7.1 nM). It can however, also act as a partial agonist of AR (EC50 = 4.0 μM). In the presence of 10 nM testosterone, low concentrations of cyproterone acetate inhibit T-stimulated transcription of 3XHRE-LUC, but at higher concentrations, transcription is stimulated. Cyproterone Acetate is also a hepatomitogen and tumor promoter and induces apoptosis in hepatocytes.
Cyproterone Acetate (CAS 427-51-0) References
Kasper, P., Mueller, L. Carcinogenesis. 20:2185-8 (1999). Oberhammer, F.A., Pavelka, M., Sharma, S., et al. Proc. Natl Acad Sci, USA. 89:5408-12 (1992).Inhibitor of:
17β-HSD6, Androgen Receptor, Choriogonadotropin β, DHRS7, EG623898, GLCCI1, Kap, MISR II, mPRε, MUP1, MUP11, OTTMUSG00000008394, SHBG, TCP-11, TEX30, and Tsx.Activator of:
Sna.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cyproterone Acetate, 100 mg | sc-204703 | 100 mg | $60.00 | |||
Cyproterone Acetate, 250 mg | sc-204703A | 250 mg | $199.00 |