Cyproconazole (CAS 94361-06-5)

Cyproconazole is a triazole fungicide with a mechanism of action centered on inhibiting the biosynthesis of ergosterol, a crucial component of fungal cell membranes. Specifically, it targets the enzyme lanosterol 14α-demethylase (CYP51), which is essential for the conversion of lanosterol to ergosterol. By blocking this enzyme, cyproconazole disrupts the synthesis of ergosterol, leading to the accumulation of abnormal sterols and ultimately causing fungal cell death. In scientific research, cyproconazole has been extensively utilized to study fungal physiology and pathogenicity, particularly in agricultural and environmental contexts. It serves as a valuable tool for investigating the mechanisms of antifungal resistance, providing insights into the molecular basis of resistance mechanisms and guiding the development of strategies to combat fungal diseases in crops. Furthermore, cyproconazole is employed in ecological studies to assess its impact on non-target organisms, such as soil microbiota and aquatic ecosystems, helping to evaluate its environmental safety and potential ecological risks. Additionally, it is used in plant pathology research to explore its efficacy against various fungal pathogens and to explain the underlying mechanisms of fungicidal activity. Overall, cyproconazole plays a crucial role in advancing our understanding of fungal biology and in developing sustainable approaches for fungal disease management in agricultural systems.