Molecular structure of Cypermethrin, solid, CAS Number: 52315-07-8
Cypermethrin, solid (CAS 52315-07-8)
See product citations (10)
Application:
Cypermethrin, solid is a potent inhibitor of calcineurin
CAS Number:
52315-07-8
Purity:
≥96%
Molecular Weight:
416.3
Molecular Formula:
C22H19Cl2NO3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Cypermethrin, solid is a synthetic compound that affects the Na+ ion channels on nerve cell membranes. It is a potent PP2B (calcineurin) inhibitor (IC50~0.03 nM). It may also have varied effects on ion channels. Cypermethrin, solid toxicology depends on the precise ratio of cis- and trans-species present in commercial mixtures - for example a mitxure of 80:20 cis-trans species shows different toxicology to a mixture of 40:60 cis-trans species. Pure isomers of Cypermethrin form a solid while a mixture of isomers of Cypermethrin, solid form a semi-solid or liquid.
Cypermethrin, solid (CAS 52315-07-8) References
- Specific inhibition of calcineurin by type II synthetic pyrethroid insecticides. | Enan, E. and Matsumura, F. 1992. Biochem Pharmacol. 43: 1777-84. PMID: 1315545
- Nerve membrane Na+ channels as targets of insecticides. | Narahashi, T. 1992. Trends Pharmacol Sci. 13: 236-41. PMID: 1321523
- Cypermethrin induced toxicities in fish and adverse health outcomes: Its prevention and control measure adaptation. | Ullah, S., et al. 2018. J Environ Manage. 206: 863-871. PMID: 29202434
- Ototoxicity of cypermethrin in Wistar rats. | Cunha, EO., et al. 2020. Braz J Otorhinolaryngol. 86: 587-592. PMID: 31122882
- Fate of cypermethrin in Malaysian oil palm plantation. | Sulaiman, N., et al. 2020. Drug Test Anal. 12: 504-513. PMID: 31898859
- Cypermethrin-induced cortical neurons apoptosis via the Nrf2/ARE signaling pathway. | Zhou, L., et al. 2020. Pestic Biochem Physiol. 165: 104547. PMID: 32359539
- Cypermethrin Induces the Activation of Rat Primary Microglia and Expression of Inflammatory Proteins. | Mishra, S., et al. 2021. J Mol Neurosci. 71: 1275-1283. PMID: 33230707
- Combination of cypermethrin and thymol for control of Rhipicephalus microplus: Efficacy evaluation and description of an action mechanism. | Tavares, CP., et al. 2022. Ticks Tick Borne Dis. 13: 101874. PMID: 34839252
- Cypermethrin inhibits Leydig cell development and function in pubertal rats. | Li, S., et al. 2022. Environ Toxicol. 37: 1160-1172. PMID: 35102696
- Do cypermethrin and fenvalerate disturb the function of the bovine cervix in vitro? | Wrobel, MH., et al. 2022. J Endocrinol. 253: 133-142. PMID: 35343441
- Indigenous bacterial consortium-mediated cypermethrin degradation in the presence of organic amendments and Zea mays plants. | Bhatt, P., et al. 2022. Environ Res. 212: 113137. PMID: 35358545
- Inhibition of phosphatase 2B prevents expression of hippocampal long-term potentiation. | Wang, JH. and Stelzer, A. 1994. Neuroreport. 5: 2377-80. PMID: 7881062
- Class II pyrethroids: noninhibitors calcineurin. | Enz, A. and Pombo-Villar, E. 1997. Biochem Pharmacol. 54: 321-3. PMID: 9271338
Inhibitor of:
PP2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cypermethrin, solid, 10 mg | sc-24012 | 10 mg | $35.00 |