Date published: 2026-4-29

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CYM 5442 hydrochloride (CAS 1783987-80-3)

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Application:
CYM 5442 hydrochloride is a potent, brain penetrant, and selective EDG-1 (S1P1) agonist
CAS Number:
1783987-80-3
Purity:
≥98%
Molecular Weight:
445.94
Molecular Formula:
C23H27N3O4•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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CYM 5442 hydrochloride is a compound extensively studied in the field of immunology and cell signaling. This compound is known as a selective agonist for the sphingosine-1-phosphate receptor 1 (S1P1), which is a G protein-coupled receptor involved in the regulation of endothelial cell barrier function and lymphocyte trafficking. Research involving CYM 5442 hydrochloride focuses on elucidating the role of S1P1 in immune response and vascular integrity. Studies also investigate the potential of CYM 5442 hydrochloride to modulate lymphocyte circulation patterns and its effects on the inflammatory response. Furthermore, this compound is used to explore the signaling mechanisms underlying S1P1 receptor activation and its downstream biological effects.


CYM 5442 hydrochloride (CAS 1783987-80-3) References

  1. Full pharmacological efficacy of a novel S1P1 agonist that does not require S1P-like headgroup interactions.  |  Gonzalez-Cabrera, PJ., et al. 2008. Mol Pharmacol. 74: 1308-18. PMID: 18708635

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

CYM 5442 hydrochloride, 10 mg

sc-311309
10 mg
$218.00

CYM 5442 hydrochloride, 50 mg

sc-311309A
50 mg
$905.00