Date published: 2025-9-6

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Cyclosporin B (CAS 63775-95-1)

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Alternate Names:
Ala2-cyclosporine; Antibiotic S 7481F2
Application:
Cyclosporin B is a group of nonpolar cyclic oligopeptides
CAS Number:
63775-95-1
Molecular Weight:
1188.58
Molecular Formula:
C61H109N11O12
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cyclosporin B is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosuppressant activity.


Cyclosporin B (CAS 63775-95-1) References

  1. Cyclosporine A and FK506 induce osteoclast apoptosis in mouse bone marrow cell cultures.  |  Igarashi, K., et al. 2004. Bone. 35: 47-56. PMID: 15207740
  2. Liquid chromatographic-electrospray mass spectrometric determination of cyclosporin A in human plasma.  |  Zaater, MF., et al. 2005. Anal Bioanal Chem. 382: 223-30. PMID: 15900476
  3. Determination of cyclosporine and its metabolites in blood via HPLC-MS and correlation to clinically important parameters.  |  Vollenbroeker, B., et al. 2005. Transplant Proc. 37: 1741-4. PMID: 15919451
  4. [Complex of cyclosporins produced by Tolypocladium inflatum isolated from soil sample from Buriatiia].  |  Bibikova, MV., et al. 2009. Antibiot Khimioter. 54: 6-9. PMID: 20415255
  5. Evaluation and identification of hepatitis B virus entry inhibitors using HepG2 cells overexpressing a membrane transporter NTCP.  |  Iwamoto, M., et al. 2014. Biochem Biophys Res Commun. 443: 808-13. PMID: 24342612
  6. Cyclosporins, fungal metabolites with immunosuppressive activities.  |  von Wartburg, A. and Traber, R. 1988. Prog Med Chem. 25: 1-33. PMID: 3076967
  7. Diversity and toxigenicity of fungi and description of Fusarium madaense sp. nov. from cereals, legumes and soils in north-central Nigeria.  |  Ezekiel, CN., et al. 2020. MycoKeys. 67: 95-124. PMID: 32565683
  8. In vitro screening of 65 mycotoxins for insecticidal potential.  |  Boguś, MI., et al. 2021. PLoS One. 16: e0248772. PMID: 33735295
  9. Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2.  |  Dittmar, M., et al. 2021. Cell Rep. 35: 108959. PMID: 33811811
  10. Metabolite Formation by Fungal Pathogens of Potatoes (Solanum tuberosum L.) in the Presence of Bioprotective Agents.  |  Steglińska, A., et al. 2023. Int J Environ Res Public Health. 20: PMID: 36982130

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cyclosporin B, 5 mg

sc-204701
5 mg
$1440.00

What is the appearance of the chemical?

Asked by: two2igm05
Thank you for your question. The compound, sc-204701, is provided as a white crystalline powder. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com. or using the Live Chat function on our website.
Answered by: Tech Service 8
Date published: 2018-04-13
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Rated 5 out of 5 by from Various publications cite the use of theVarious publications cite the use of the immunosuppressant Cyclosporin B in organ transplantation to prevent graft rejection. -SCBT Publication Review
Date published: 2015-01-14
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Cyclosporin B is rated 5.0 out of 5 by 1.
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