Date published: 2026-5-29

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Cyclosporin AM 1 (CAS 89270-28-0)

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Alternate Names:
Cyclosporin A Metabolite 17; Hydroxycyclosporine
Application:
Cyclosporin AM 1 is a cyclosporine metabolite
CAS Number:
89270-28-0
Molecular Weight:
1218.61
Molecular Formula:
C62H111N11O13
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cyclosporin AM 1 interacts with cellular components by inhibiting the activity of calcineurin, a calcium-dependent phosphatase enzyme. This inhibition prevents the dephosphorylation of nuclear factor of activated T-cells (NFAT). By disrupting this pathway, Cyclosporin AM 1 effectively suppresses the immune response and reduces inflammation.Cyclosporin AM 1 targets T-cells, making it valuable for studying immune and autoimmune responses in laboratory applications. Its mechanism of action has been studied and is well understood, making it is useful for investigating the molecular pathways involved in immune regulation. Cyclosporin AM 1 plays a role in understanding the cellular processes involved in immune response and inflammation.


Cyclosporin AM 1 (CAS 89270-28-0) References

  1. Low Content of Cyclosporine A and Its Metabolites in the Colostrum of Post-Transplant Mothers.  |  Kociszewska-Najman, B., et al. 2020. Nutrients. 12: PMID: 32899873

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cyclosporin AM 1, 1 mg

sc-207472
1 mg
$480.00

Cyclosporin AM 1, 2 mg

sc-207472A
2 mg
$900.00

Cyclosporin AM 1, 5 mg

sc-207472B
5 mg
$1750.00

Cyclosporin AM 1, 10 mg

sc-207472C
10 mg
$3200.00