Cyclosporin A Antibody (B11 1.4): sc-69889
- Cyclosporin A Antibody (B11 1.4) is a mouse monoclonal IgM provided at 200 µg/ml
- raised against BSA-conjugated Cyclosporine A, a cyclic undecapeptide of fungal origin
- recommended for detection of Cyclosporine A of fungal origin by ELISA
- also provided azide-free for inhibition assays, sc-69889 L,
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Cyclosporin A Antibody (B11 1.4). This work is in progress.
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SEE ALSO...
Cyclosporin A Antibody (B11 1.4) is a mouse monoclonal IgM antibody that detects Cyclosporin A in fungal species by enzyme-linked immunosorbent assay (ELISA). Cyclosporin A, a compound derived from the fungus Tolypocladium inflatum, plays a crucial role in immunopharmacology as the first immunosuppressive drug that allowed for selective immunoregulation of T cells with minimal toxicity. This is particularly important in organ transplant procedures, where Cyclosporin A effectively reduces the risk of organ rejection by inhibiting calcineurin activity, which in turn prevents the transcription of interleukin-2 (IL-2) and dampens the immune response. Additionally, Cyclosporin A′s ability to inhibit the opening of permeability-transition pores in mitochondria highlights neuroprotective properties, making Cyclosporin A valuable in mitigating damage from head trauma and neurodegenerative diseases. Anti-Cyclosporin A antibody (B11 1.4) serves as an essential tool for researchers studying the multifaceted roles of Cyclosporin A in both immunology and neuroprotection.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cyclosporin A Antibody (B11 1.4) | sc-69889 | 200 µg/ml | $322.00 |