Cyclosomatostatin is a non-selective SSTR (somatostatin receptor) antagonist. Effects of SST are blocked on release of growth hormone, insulin and glucagon, airway β-adrenergic function, modulation of ACh release and CRF-induced suppression of gastric empyting. Cyclosomatostatin potentially acts as an SSTR agonist in human neuroblastoma cell line SH-SY5Y.
1. Fries, J.L., et al. 1982. Peptides. 3: 811-814. PMID: 6129618 2. Stirnweis, J., et al. 2002. Peptides. 23: 1503-1506. PMID: 12182954 3. Guo, Y., et al. 2008. S. Brain Res. 1229: 61-71. PMID: 18640104
Soluble in 20% acetonitrile / water (2 mg/ml), water (partly), and distilled water,If does not completely dissolve, add 0.1 M acetic acid..
Store at -20° C
1118.40° C at 760 mmHg (Predicted)
1.15 g/cm3 (Predicted)
n20D 1.56 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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