Cyclosomatostatin CAS: 84211-54-1
MF: C44H57N7O6
MW: 779.98
A non-selective somatostatin receptor antagonist.

Cyclosomatostatin (CAS 84211-54-1)

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Alternate Names: Cyclo(7-aminoheptanoyl-Phe-D-Trp-Lys-Thr[Bzl])
Application: Cyclosomatostatin is a non-selective somatostatin receptor antagonist
CAS Number: 84211-54-1
Molecular Weight: 779.98
Molecular Formula: C44H57N7O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Cyclosomatostatin is a non-selective SSTR (somatostatin receptor) antagonist. Effects of SST are blocked on release of growth hormone, insulin and glucagon, airway β-adrenergic function, modulation of ACh release and CRF-induced suppression of gastric empyting. Cyclosomatostatin potentially acts as an SSTR agonist in human neuroblastoma cell line SH-SY5Y.


References

1. Fries, J.L., et al. 1982. Peptides. 3: 811-814. PMID: 6129618
2. Stirnweis, J., et al. 2002. Peptides. 23: 1503-1506. PMID: 12182954
3. Guo, Y., et al. 2008. S. Brain Res. 1229: 61-71. PMID: 18640104

Physical State :
Solid
Sequence :
cyclo-Phe-Trp-Lys-Thr-Bzl
Solubility :
Soluble in 20% acetonitrile / water (2 mg/ml), water (partly), and distilled water,If does not completely dissolve, add 0.1 M acetic acid..
Storage :
Store at -20° C
Boiling Point :
1118.40° C at 760 mmHg (Predicted)
Density :
1.15 g/cm3 (Predicted)
Refractive Index :
n20D 1.56 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
4195535
MDL Number :
MFCD00076778
SMILES :
CC(C1C(=O)NCCCCCCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)OCC5=CC=CC=C5

Download SDS (MSDS)

Certificate of Analysis

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