Date published: 2026-1-21

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Cyclobutane-1,1-dicarboxylic acid (CAS 5445-51-2)

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CAS Number:
5445-51-2
Molecular Weight:
144.13
Molecular Formula:
C6H8O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cyclobutane-1,1-dicarboxylic acid is a compound that functions as a building block in organic synthesis. It is used to create various derivatives and polymers through its ability to undergo chemical reactions, such as esterification and condensation. Cyclobutane-1,1-dicarboxylic acid can participate in cross-coupling reactions and serve as a precursor for the synthesis of complex organic molecules. Its mechanism of action involves participating in chemical reactions that lead to the formation of new compounds with diverse properties. At the molecular level, it can undergo substitution and addition reactions, allowing for the modification of its structure to generate a wide range of products. In a research and development setting, Cyclobutane-1,1-dicarboxylic acid plays a role in the creation of novel materials and compounds through its reactivity and ability to form diverse chemical bonds.


Cyclobutane-1,1-dicarboxylic acid (CAS 5445-51-2) References

  1. Synthesis and biological activity of water-soluble maleimide derivatives of the anticancer drug carboplatin designed as albumin-binding prodrugs.  |  Warnecke, A., et al. 2004. Bioconjug Chem. 15: 1349-59. PMID: 15546202
  2. Complex formation between Ru(η(6)-p-cym)(H2O)3]2+ and (O,O) donor ligands with biological relevance in aqueous solution.  |  Bíró, L., et al. 2010. Dalton Trans. 39: 10272-8. PMID: 20922244
  3. Synthesis, antiproliferative activity and estrogen receptor α affinity of novel estradiol-linked platinum(II) complex analogs to carboplatin and oxaliplatin. Potential vector complexes to target estrogen-dependent tissues.  |  Saha, P., et al. 2012. Eur J Med Chem. 48: 385-90. PMID: 22209414
  4. Investigation of in vitro anticancer and DNA strap interactions in live cells using carboplatin type Cu(II) and Zn(II) metalloinsertors.  |  Pravin, N. and Raman, N. 2014. Eur J Med Chem. 85: 675-87. PMID: 25128669
  5. Design, synthesis and anticancer activity of diam(m)ine platinum(II) complexes bearing a small-molecular cell apoptosis inducer dichloroacetate.  |  Liu, W., et al. 2015. J Inorg Biochem. 146: 14-8. PMID: 25706321
  6. Stability and cellular studies of [rac-1,2-bis(4-fluorophenyl)-ethylenediamine][cyclobutane-1,1- dicarboxylato]platinum(II), a novel, highly active carboplatin derivative.  |  Gust, R., et al. 1998. J Cancer Res Clin Oncol. 124: 585-97. PMID: 9860287

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cyclobutane-1,1-dicarboxylic acid, 5 g

sc-257265
5 g
$49.00