Molecular structure of Cyclo(-Phe-Pro), CAS Number: 3705-26-8
Cyclo(-Phe-Pro) (CAS 3705-26-8)
Alternate Names:
Cyclo-L-phenylalanyl-L-proline
CAS Number:
3705-26-8
Molecular Weight:
244.29
Molecular Formula:
C14H16N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Cyclo(-Phe-Pro) is utilized in probing the intricacies of protein architecture and activity, as well as in enzyme studies and the exploration of peptide behavior. In biochemical studies, Cyclo(-Phe-Pro) serves as a model compound to understand the conformational stability of peptides and their interactions with other biomolecules. Moreover, Cyclo(-Phe-Pro) serves as a tool in the realm of drug discovery, aiding in the understanding of drug interactions at the molecular level. It is investigated in materials science research for its potential use in the development of peptide-based materials with novel properties.
Cyclo(-Phe-Pro) (CAS 3705-26-8) References
- Caspase-3 activation and induction of PARP cleavage by cyclic dipeptide cyclo(Phe-Pro) in HT-29 cells. | Brauns, SC., et al. 2005. Anticancer Res. 25: 4197-202. PMID: 16309216
- Cyclo(Phe-Pro) modulates the expression of ompU in Vibrio spp. | Park, DK., et al. 2006. J Bacteriol. 188: 2214-21. PMID: 16513751
- The cyclic dipeptide cyclo(Phe-Pro) inhibits cholera toxin and toxin-coregulated pilus production in O1 El Tor Vibrio cholerae. | Bina, XR. and Bina, JE. 2010. J Bacteriol. 192: 3829-32. PMID: 20453095
- Butyrolactone and cycloheptanetrione from mangrove-associated fungus Aspergillus terreus. | Shen, Y., et al. 2012. Chem Pharm Bull (Tokyo). 60: 1437-41. PMID: 23124567
- Vibrio cholerae ToxR downregulates virulence factor production in response to cyclo(Phe-Pro). | Bina, XR., et al. 2013. mBio. 4: e00366-13. PMID: 23982069
- Quantification of cyclic dipeptides from cultures of Lactobacillus brevis R2Δ by HRGC/MS using stable isotope dilution assay. | Axel, C., et al. 2014. Anal Bioanal Chem. 406: 2433-44. PMID: 24477717
- Cyclo(Phe-Pro) produced by the human pathogen Vibrio vulnificus inhibits host innate immune responses through the NF-κB pathway. | Kim, K., et al. 2015. Infect Immun. 83: 1150-61. PMID: 25561711
- Vibrio vulnificus quorum-sensing molecule cyclo(Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity. | Lee, W., et al. 2018. Nat Commun. 9: 1606. PMID: 29686409
- Streptomyces nigra sp. nov. Is a Novel Actinobacterium Isolated From Mangrove Soil and Exerts a Potent Antitumor Activity in Vitro. | Chen, C., et al. 2018. Front Microbiol. 9: 1587. PMID: 30072967
- Cyclo(Phe-Pro) produced by Vibrio species passes through biological membranes by simple diffusion. | Park, NY., et al. 2020. Appl Microbiol Biotechnol. 104: 6791-6798. PMID: 32533306
- Vibrio vulnificus induces the death of a major bacterial species in the mouse gut via cyclo-Phe-Pro. | Kim, JA., et al. 2021. Microbiome. 9: 161. PMID: 34284824
- Unambiguous Stereochemical Assignment of Cyclo(Phe-Pro), Cyclo(Leu-Pro), and Cyclo(Val-Pro) by Electronic Circular Dichroic Spectroscopy. | Domzalski, A., et al. 2021. Molecules. 26: PMID: 34641525
- Streptococcus mutans and Candida albicans Biofilm Inhibitors Produced by Lactiplantibacillus plantarum CCFM8724. | Li, J., et al. 2022. Curr Microbiol. 79: 143. PMID: 35325333
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cyclo(-Phe-Pro), 250 mg | sc-294124 | 250 mg | $326.00 | |||
Cyclo(-Phe-Pro), 1 g | sc-294124A | 1 g | $933.00 |