Molecular structure of Cyclo(-Phe-Phe), CAS Number: 2862-51-3
Cyclo(-Phe-Phe) (CAS 2862-51-3)
See product citations (1)
Alternate Names:
3,6-Dibenzyl-2,5-piperazinedione; Cyclo(L-Phe-L-Phe)
CAS Number:
2862-51-3
Molecular Weight:
294.35
Molecular Formula:
C18H18N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Cyclo(-Phe-Phe), also known as Cyclo(phenylalanyl-phenylalanyl) or CPP, is a cyclic dipeptide consisting of two phenylalanine molecules connected by a peptide bond. This simple peptide has been explored for its various biochemical and physiological effects. Its potential as a delivery agent in scientific studies has also been examined. Cyclo(-Phe-Phe) has been utilized in research around cell membrane interactions, protein folding, and delivery mechanisms. Cyclo(-Phe-Phe) has displayed interactions with cell membranes and proteins in diverse manners. It has been observed to bind to cell membranes and proteins, modulating their activity, and aiding in the transportation of other molecules across cell membranes.
Cyclo(-Phe-Phe) (CAS 2862-51-3) References
- Efficient microwave assisted syntheses of 2,5-diketopiperazines in aqueous media. | Pérez-Picaso, L., et al. 2009. Molecules. 14: 2836-49. PMID: 19701127
- Prolyl aminopeptidase from Streptomyces thermoluteus subsp. fuscus strain NBRC14270 and synthesis of proline-containing peptides by its S144C variant. | Yamamoto, Y., et al. 2010. Appl Environ Microbiol. 76: 6180-5. PMID: 20675455
- A prospective study of serum metabolites and colorectal cancer risk. | Cross, AJ., et al. 2014. Cancer. 120: 3049-57. PMID: 24894841
- Serum metabolic signatures of primary biliary cirrhosis and primary sclerosing cholangitis. | Bell, LN., et al. 2015. Liver Int. 35: 263-74. PMID: 25181933
- Expanding the chemical space for natural products by Aspergillus-Streptomyces co-cultivation and biotransformation. | Wu, C., et al. 2015. Sci Rep. 5: 10868. PMID: 26040782
- A Simple Defined Medium for the Production of True Diketopiperazines in Xylella fastidiosa and Their Identification by Ultra-Fast Liquid Chromatography-Electrospray Ionization Ion Trap Mass Spectrometry. | Silva, MMD., et al. 2017. Molecules. 22: PMID: 28608830
- Microbial diversity of saline environments: searching for cytotoxic activities. | Díaz-Cárdenas, C., et al. 2017. AMB Express. 7: 223. PMID: 29273919
- Protective effects of diketopiperazines from Moslae Herba against influenza A virus-induced pulmonary inflammation via inhibition of viral replication and platelets aggregation. | Zhang, HH., et al. 2018. J Ethnopharmacol. 215: 156-166. PMID: 29309861
- Novel Polyethers from Screening Actinoallomurus spp. | Iorio, M., et al. 2018. Antibiotics (Basel). 7: PMID: 29904034
- Non-ribosomal Peptide Synthetase Gene Clusters in the Human Pathogenic Fungus Scedosporium apiospermum. | Le Govic, Y., et al. 2019. Front Microbiol. 10: 2062. PMID: 31551992
- Comparative studies on similarities and differences of cyclodipeptide oxidases for installation of C-C double bonds at the diketopiperazine ring. | Mikulski, L., et al. 2020. Appl Microbiol Biotechnol. 104: 2523-2536. PMID: 31989220
- Bioactive Potential of Extracts of Labrenzia aggregata Strain USBA 371, a Halophilic Bacterium Isolated from a Terrestrial Source. | Díaz-Cárdenas, C., et al. 2020. Molecules. 25: PMID: 32486092
- Hydrolyzed Chicken Meat Extract Attenuates Neuroinflammation and Cognitive Impairment in Middle-Aged Mouse by Regulating M1/M2 Microglial Polarization. | Ni, L., et al. 2021. J Agric Food Chem. 69: 9800-9812. PMID: 34404209
- Integration of In Silico and In Vitro Analysis of Gliotoxin Production Reveals a Narrow Range of Producing Fungal Species. | Redrado, S., et al. 2022. J Fungi (Basel). 8: PMID: 35448592
- Cyclo(-Phe-Phe) alleviates chick embryo liver injury via activating the Nrf2 pathway. | Zhang, QY., et al. 2022. Food Funct. 13: 6962-6974. PMID: 35678194
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cyclo(-Phe-Phe), 250 mg | sc-285318 | 250 mg | $288.00 | |||
Cyclo(-Phe-Phe), 1 g | sc-285318A | 1 g | $571.00 |