Date published: 2026-4-30

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Cyclo(-Ala-Ala) (CAS 5845-61-4)

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Alternate Names:
Ala-Ala diketopiperazin
CAS Number:
5845-61-4
Molecular Weight:
142.16
Molecular Formula:
C6H10N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cyclo(-Ala-Ala) is a cyclic dipeptide that functions as a molecular scaffold in development applications. It is known to interact with specific cellular targets, modulating their activity and influencing downstream signaling pathways. Cyclo(-Ala-Ala) has the ability to bind to proteins and enzymes, altering their conformation and affecting their function within the cellular environment. Cyclo(-Ala-Ala) may play a role in the regulation of various biological processes, including cell growth, differentiation, and apoptosis. Its mechanism of action involves the disruption of protein-protein interactions and the inhibition of enzymatic activity, ultimately leading to changes in cellular behavior. Cyclo(-Ala-Ala) is utilized to study the molecular mechanisms underlying various physiological and pathological processes, providing insights into potential targets.


Cyclo(-Ala-Ala) (CAS 5845-61-4) References

  1. Thermodynamic characterization of the osmolyte effect on protein stability and the effect of GdnHCl on the protein denatured state.  |  Venkatesu, P., et al. 2007. J Phys Chem B. 111: 9045-56. PMID: 17602514
  2. Thermodynamic characterization of the biocompatible ionic liquid effects on protein model compounds and their functional groups.  |  Attri, P. and Venkatesu, P. 2011. Phys Chem Chem Phys. 13: 6566-75. PMID: 21369576
  3. Synchrotron vacuum ultraviolet (VUV) photo-induced fragmentation of cyclic dipeptides radical cations.  |  Zhang, L., et al. 2012. Amino Acids. 43: 279-87. PMID: 21918875
  4. Chiral gas chromatography of 2,5-diketopiperazines following a ring-opening derivatization method for complete isomeric separation.  |  Mimura, K., et al. 2018. J Chromatogr A. 1566: 118-123. PMID: 29954611
  5. 17O and 14N n.m.r. studies of the Co (II) interaction with cyclo(Ala*-Ala) in aqueous solution.  |  Tritt-Goc, J., et al. 1987. Int J Pept Protein Res. 29: 406-14. PMID: 3596898
  6. Theoretical pi-pi* absorption and circular dichroic spectra of cyclic dipeptides.  |  Sathyanarayana, BK. and Applequist, J. 1985. Int J Pept Protein Res. 26: 518-27. PMID: 4086166

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cyclo(-Ala-Ala), 250 mg

sc-294115
250 mg
$131.00

Cyclo(-Ala-Ala), 1 g

sc-294115A
1 g
$258.00