Molecular structure of Cyclizine Hydrochloride, CAS Number: 303-25-3
Cyclizine Hydrochloride (CAS 303-25-3)
Alternate Names:
1-(Diphenylmethyl)-4-methylpiperazine Hydrochloride; Marezine Hydrochloride; Marzine
Application:
Cyclizine Hydrochloride is a piperazine derivative with anti-emetic activity
CAS Number:
303-25-3
Molecular Weight:
302.84
Molecular Formula:
C18H22N2•HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Cyclizine is a piperazine derivative with anti-emetic activity that is useful in the prevention and treatment of nausea and vomiting associated with motion sickness. Cyclizine Hydrochloride is an activator of Histamine H1 Receptor.
Cyclizine Hydrochloride (CAS 303-25-3) References
- Effect of meclizine hydrochloride (bonamine) upon vestibular function; observations with notes on its value in comparison with cyclizine hydrochloride (marezine) and dimenhydrinate (dramamine). | GUTNER, LB., et al. 1955. AMA Arch Otolaryngol. 62: 497-503. PMID: 13268159
- Antagonism of apomorphine-induced pecking in pigeons. | DHAWAN, BN., et al. 1961. Br J Pharmacol Chemother. 16: 137-45. PMID: 13722430
- The determination of ergotamine in preparations containing ergotamine tartrate and cyclizine hydrochloride. | CAWS, AC. and LAWRENCE, BE. 1962. J Pharm Pharmacol. 14(Suppl): 59T-62T. PMID: 14019504
- A capillary zone electrophoresis (CZE) method for the determination of cyclizine hydrochloride in tablets and suppositories. | Mohammadi, A., et al. 2004. J Pharm Biomed Anal. 35: 233-9. PMID: 15030899
- Application of adsorptive voltammetry for the detection of sub-nano molar cyclizine in biological fluids and tablets using fast Fourier transform continuous cyclic voltammetry in a flowing system. | Norouzi, P., et al. 2009. Anal Sci. 25: 505-10. PMID: 19359790
- The effects of H1-antihistamines on the nitric oxide production by RAW 264.7 cells with respect to their lipophilicity. | Králová, J., et al. 2009. Int Immunopharmacol. 9: 990-5. PMID: 19362170
- Bupivacaine-induced cardiotoxicity in hypoxic and acidotic sheep. | Rosen, MA., et al. 1985. Anesth Analg. 64: 1089-96. PMID: 4051206
- Pharmacological characterization of cardiac histamine receptors: sensitivity to H1-receptor antagonists. | Levi, R. and Kuye, JO. 1974. Eur J Pharmacol. 27: 330-8. PMID: 4153866
- Benzhydrylpiperazine antihistamines, hydramnios, and congenital malformations in the rat. | King, CT., et al. 1965. Am J Obstet Gynecol. 93: 563-5. PMID: 4378853
- pKa determination of benzhydrylpiperazine antihistamines in aqueous and aqueous methanol solutions. | Newton, DW., et al. 1982. J Pharm Sci. 71: 1363-6. PMID: 6130141
- Morphological and immunocytochemical study of rat pancreatic beta cell changes induced by cyclizine. | Hanai, N. 1984. J Appl Toxicol. 4: 308-14. PMID: 6394638
- Analysis of some commercial preparations for migraine treatment using ion-pair high-performance liquid chromatography with addition of salts to the mobile phase. | Low, GK., et al. 1983. J Chromatogr. 261: 345-56. PMID: 6874803
- Assay of procyclidine hydrochloride, cyclizine hydrochloride and diethylcarbamazine citrate in tablets using ion-responsive electrodes. | Campbell, MJ., et al. 1980. Analyst. 105: 605-11. PMID: 7416480
Activator of:
Histamine H1 Receptor.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cyclizine Hydrochloride, 1 g | sc-391816 | 1 g | $306.00 |