Date published: 2026-2-18

1-800-457-3801

SCBT Portrait Logo
Seach Input

(±)Cyanopindolol hemifumarate (CAS 69906-85-0)

0.0(0)
Write a reviewAsk a question

CAS Number:
69906-85-0
Molecular Weight:
345.4
Molecular Formula:
C16H21N3O21/2C4H4O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Cyanopindolol hemifumarate is a beta-adrenergic antagonist that functions by competitively inhibiting the binding of catecholamines to beta-adrenergic receptors in cells. (±)Cyanopindolol Hemifumarate′s mechanism of action involves blocking the activation of beta-adrenergic receptors, which are G protein-coupled receptors found on the surface of many cell types. By doing so, it interferes with the downstream signaling pathways that are typically activated by catecholamines, ultimately leading to a reduction in the cellular response to sympathetic nervous system stimulation. (±)Cyanopindolol Hemifumarate′s functional role in development applications lies in its ability to selectively modulate beta-adrenergic receptor activity, allowing for the investigation of the specific cellular and molecular processes influenced by these receptors. Its competitive binding to beta-adrenergic receptors may be a useful for studying the physiological and pathological roles of these receptors in various experimental models.


(±)Cyanopindolol hemifumarate (CAS 69906-85-0) References

  1. Methiothepin attenuates gastric secretion and motility effects of vagal stimulants at the dorsal vagal complex.  |  Varanasi, S., et al. 2002. Eur J Pharmacol. 436: 67-73. PMID: 11834248
  2. Serotonergic control of cerebellar mossy fiber activity by modulation of signal transfer by rat pontine nuclei neurons.  |  Möck, M., et al. 2002. J Neurophysiol. 88: 549-64. PMID: 12163509
  3. Pharmacological characterization of 5-HT(1B) receptor-mediated inhibition of local excitatory synaptic transmission in the CA1 region of rat hippocampus.  |  Mlinar, B., et al. 2003. Br J Pharmacol. 138: 71-80. PMID: 12522075
  4. Stress impairs 5-HT2A receptor-mediated serotonergic facilitation of GABA release in juvenile rat basolateral amygdala.  |  Jiang, X., et al. 2009. Neuropsychopharmacology. 34: 410-23. PMID: 18536707
  5. The role of spinal serotonin receptor and alpha adrenoceptor on the antiallodynic effects induced by intrathecal milnacipran in chronic constriction injury rats.  |  Nakamura, T., et al. 2014. Eur J Pharmacol. 738: 57-65. PMID: 24876059
  6. 4-EA-NBOMe, an amphetamine derivative, alters glutamatergic synaptic transmission through 5-HT1A receptors on cortical neurons from SpragueDawley rat and pyramidal neurons from C57BL/6 mouse.  |  Oh, HA., et al. 2023. Neurotoxicology. 95: 144-154. PMID: 36738894
  7. 5-HT7 receptors mediate serotonergic effects on light-sensitive suprachiasmatic nucleus neurons.  |  Ying, SW. and Rusak, B. 1997. Brain Res. 755: 246-54. PMID: 9175892

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(±)Cyanopindolol hemifumarate, 10 mg

sc-471422
10 mg
$104.00