Cyanine 3-UTP
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Cyanine 3-UTP, also known as Cy3-UTP, serves as a substitute for UTP in the presence of T7 RNA polymerase, enabling the generation of labeled probes through in vitro transcription. These probes exhibit orange fluorescence upon assembly of mRNA incorporating Cyanine 3-UTP. Furthermore, the resulting Cy3-labeled mRNA can be visualized under ultraviolet light without the need for additional staining after gel electrophoresis. These probes, when combined with cyanine 3-UTP, are particularly suited for multicolor fluorescence analysis, such as dual-color expression arrays. As a result, Cyanine 3 labeled RNA probes find extensive utility in various molecular biology applications, including in situ hybridization and gene expression microarrays.
Cyanine 3-UTP References
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- The cell biology of Tobacco mosaic virus replication and movement. | Liu, C. and Nelson, RS. 2013. Front Plant Sci. 4: 12. PMID: 23403525
- KRAS mutational subtype and copy number predict in vitro response of human pancreatic cancer cell lines to MEK inhibition. | Hamidi, H., et al. 2014. Br J Cancer. 111: 1788-801. PMID: 25167228
- Self-assembled Messenger RNA Nanoparticles (mRNA-NPs) for Efficient Gene Expression. | Kim, H., et al. 2015. Sci Rep. 5: 12737. PMID: 26235529
- Cocaine Administration and Its Withdrawal Enhance the Expression of Genes Encoding Histone-Modifying Enzymes and Histone Acetylation in the Rat Prefrontal Cortex. | Sadakierska-Chudy, A., et al. 2017. Neurotox Res. 32: 141-150. PMID: 28393332
- Increased 5-hydroxymethylation levels in the hippocampus of rat extinguished from cocaine self-administration. | Sadakierska-Chudy, A., et al. 2017. Hippocampus. 27: 811-821. PMID: 28422379
- Influenza A Virus NS1 Protein Promotes Efficient Nuclear Export of Unspliced Viral M1 mRNA. | Pereira, CF., et al. 2017. J Virol. 91: PMID: 28515301
- Hepatic differentiation of mouse bone marrow‑derived mesenchymal stem cells using a novel 3D culture system. | Wu, Q., et al. 2017. Mol Med Rep. 16: 9473-9479. PMID: 29152658
- The NMDA Receptor Subunit (GluN1 and GluN2A) Modulation Following Different Conditions of Cocaine Abstinence in Rat Brain Structures. | Smaga, I., et al. 2021. Neurotox Res. 39: 556-565. PMID: 33759085
- Spray-Induced Gene Silencing as a Potential Tool to Control Potato Late Blight Disease. | Kalyandurg, PB., et al. 2021. Phytopathology. 111: 2168-2175. PMID: 33973799
- Self-assembled small messenger RNA nanospheres for efficient therapeutic apoptin expression and synergistic Gene-Chemotherapy of breast cancer. | Tang, Y., et al. 2021. J Colloid Interface Sci. 603: 191-198. PMID: 34192626
- Hypoxia induces transgenerational epigenetic inheritance of small RNAs. | Wang, SY., et al. 2022. Cell Rep. 41: 111800. PMID: 36516753
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cyanine 3-UTP, 250 nmol | sc-499471 | 250 nmol | $434.00 |