Date published: 2026-5-31

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CV 1808 (CAS 53296-10-9)

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Alternate Names:
2-Phenylaminoadenosine
Application:
CV 1808 is an Adenosine A2-R agonist
CAS Number:
53296-10-9
Molecular Weight:
358.36
Molecular Formula:
C16H18N6O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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CV 1808 is an adenosine A2 receptor agonist.


CV 1808 (CAS 53296-10-9) References

  1. Afferent arteriolar adenosine A2a receptors are coupled to KATP in in vitro perfused hydronephrotic rat kidney.  |  Tang, L., et al. 1999. Am J Physiol. 277: F926-33. PMID: 10600940
  2. Role of adenosine in sleep and temperature regulation in the preoptic area of rats.  |  Ticho, SR. and Radulovacki, M. 1991. Pharmacol Biochem Behav. 40: 33-40. PMID: 1780343
  3. Adenosine and 2-phenylaminoadenosine (CV-1808) inhibit human neutrophil bactericidal function.  |  Hardart, GE., et al. 1991. Infect Immun. 59: 885-9. PMID: 1847698
  4. Afferent arteriolar vasodilator effect of adenosine predominantly involves adenosine A2B receptor activation.  |  Feng, MG. and Navar, LG. 2010. Am J Physiol Renal Physiol. 299: F310-5. PMID: 20462966
  5. Hemodynamic effects of adenosine agonists in the conscious spontaneously hypertensive rat.  |  Webb, RL., et al. 1990. J Pharmacol Exp Ther. 254: 1090-9. PMID: 2203898
  6. Combined treatment with hyaluronan inhibitor Pep-1 and a selective adenosine A2 receptor agonist reduces inflammation in experimental arthritis.  |  Campo, GM., et al. 2013. Innate Immun. 19: 462-78. PMID: 23283732
  7. Comparison of the behavioral effects of adenosine agonists and dopamine antagonists in mice.  |  Heffner, TG., et al. 1989. Psychopharmacology (Berl). 98: 31-7. PMID: 2498959
  8. Inhibition of small HA fragment activity and stimulation of A2A adenosine receptor pathway limit apoptosis and reduce cartilage damage in experimental arthritis.  |  Campo, GM., et al. 2015. Histochem Cell Biol. 143: 531-43. PMID: 25511416
  9. CGS 21680C, an A2 selective adenosine receptor agonist with preferential hypotensive activity.  |  Hutchison, AJ., et al. 1989. J Pharmacol Exp Ther. 251: 47-55. PMID: 2795469
  10. Effect of 2-phenylaminoadenosine (CV-1808) on ischemic ST-segment elevation in anesthetized dogs.  |  Matsumoto, N., et al. 1981. J Cardiovasc Pharmacol. 3: 1184-92. PMID: 6173517
  11. Inhibition of coronary circulatory failure and thromboxane A2 release during coronary occlusion and reperfusion by 2-phenylaminoadenosine (CV-1808) in anesthetized dogs.  |  Tanabe, M., et al. 1984. J Cardiovasc Pharmacol. 6: 442-8. PMID: 6202970
  12. Interaction of 2-phenylaminoadenosine (CV 1808) with adenosine systems in rat tissues.  |  Taylor, DA. and Williams, M. 1982. Eur J Pharmacol. 85: 335-8. PMID: 6295788
  13. Adenosine receptor activation modulates intraocular pressure in rabbits.  |  Crosson, CE. 1995. J Pharmacol Exp Ther. 273: 320-6. PMID: 7714784
  14. Adenosine produces pulmonary vasodilation in the perfused rabbit lung via an adenosine A2 receptor.  |  Pearl, RG. 1994. Anesth Analg. 79: 46-51. PMID: 8010453
  15. Characterization of ocular hypertension induced by adenosine agonists.  |  Crosson, CE. and Gray, T. 1996. Invest Ophthalmol Vis Sci. 37: 1833-9. PMID: 8759351

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

CV 1808, 10 mg

sc-203556
10 mg
$90.00

CV 1808, 50 mg

sc-203556A
50 mg
$350.00