CV 1808 is an Adenosine A2-R agonist, potent coronary vasodilator; weak inhibitor of adenosine uptake by rat cerebral cortical synaptosomes.
Marumoto et al (1975) Synthesis and coronary vasodilating activity of 2-substituted adenosines. Chem.Pharm.Bull. 23 759. Abiru et al (1991) The antihypertensive effect of 2-alkynyladenosines and the selective affinity for adenosine A2 receptors. Eur.J.Pha
Soluble in methanol (hot), absolute ethanol (slightly), 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin (3.6 mg/ml), and DMSO (10 mM). Insoluble in water.
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