Curcumin β-D-Glucuronide (CAS 227466-72-0)
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Curcumin β-D-Glucuronide is a biologically significant glucuronide conjugate of curcumin, extensively used in various biochemical and pharmacokinetic studies. This compound is pivotal for understanding the metabolism and disposition of curcumin in the body, as it represents one of the major metabolites formed through the glucuronidation pathway. In liver microsomes and intestinal microbiota, enzymes like UDP-glucuronosyltransferases catalyze the attachment of glucuronic acid to curcumin, transforming it into Curcumin β-D-Glucuronide. This process significantly impacts the solubility and excretion profile of curcumin, rendering Curcumin β-D-Glucuronide a marker for the bioavailability and clearance studies of its parent compound. In research applications, studying this conjugate helps elucidate the dynamics of curcumin in biological systems, offering insights into its biotransformation and the mechanisms underlying its extensive metabolism.
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Curcumin β-D-Glucuronide, 1 mg | sc-396343 | 1 mg | $398.00 |