Date published: 2025-12-10

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Cucurbit[6]uril hydrate (CAS 80262-44-8)

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Application:
Cucurbit[6]uril hydrate is a host molecule forming host-guest complexes
CAS Number:
80262-44-8
Purity:
≥95%
Molecular Weight:
996.82 (anhydrous basis)
Molecular Formula:
C36H36N24O12•xH2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cucurbit[6]uril hydrate is a compound that forms cavitands for host-guest complexation. Cavitands formed with Cucurbit[6]uril have been described to host small molecules, transition metals and lanthanides, and intercalating Pt(II) complexes. Cucurbit[6]uril is also described to increase the cytotoxicity of some Pt(II)-based intercalators, and as Cucurbit[n]uril (n = 6, 7, 8) compounds were further shown to prevent metal complex degradation by glutathione, they have been indicated as potential drug delivery cavitands of interest. Cucurbit[6]uril has also been described to form highly symmetric columnar channels as hydrate crystals.


Cucurbit[6]uril hydrate (CAS 80262-44-8) References

  1. Lanthanide complexes with cucurbit[n]urils (n = 5, 6, 7) and perrhenate ligands: new examples of encapsulation of perrhenate anions.  |  Thuéry, P. 2009. Inorg Chem. 48: 4497-513. PMID: 19354272
  2. Enhanced efficiency of the visible-light photocatalytic hydrogen generation by the ruthenium tris(2,2'-bipyridyl)-methyl viologen system in the presence of cucurbit[n]urils.  |  Silva, CG., et al. 2009. Photochem Photobiol Sci. 8: 1650-4. PMID: 20024161
  3. A general pH-responsive supramolecular nanovalve based on mesoporous organosilica hollow nanospheres.  |  Guo, W., et al. 2010. Chemistry. 16: 8641-6. PMID: 20593447
  4. Second-sphere tethering of rare-earth ions to cucurbit[6]uril by iminodiacetic acid involving carboxylic group encapsulation.  |  Thuéry, P. 2010. Inorg Chem. 49: 9078-85. PMID: 20815367
  5. Cucurbit[6]uril p-xylylenediammonium diiodide deca-hydrate inclusion complex.  |  Huang, WH., et al. 2008. Acta Crystallogr Sect E Struct Rep Online. 64: o1321-2. PMID: 21202946
  6. Thermoresponsive gold nanoshell@mesoporous silica nano-assemblies: an XPS/NMR survey.  |  Soulé, S., et al. 2015. Phys Chem Chem Phys. 17: 28719-28. PMID: 26447146
  7. A Sample Preparation Technique Using Biocompatible Composites for Biomedical Applications.  |  Liu, H., et al. 2019. Molecules. 24: PMID: 30987247
  8. An enhanced recyclable 3D adsorbent for diverse bio-applications using biocompatible magnetic nanomulberry and cucurbituril composites.  |  Luan, Y., et al. 2020. Sci Rep. 10: 443. PMID: 31949259
  9. Insight into the effects of electrochemical factors on host-guest interaction induced signature events in a biological nanopore.  |  Wei, X., et al. 2020. Nanotechnol Precis Eng. 3: 2-8. PMID: 33786424
  10. Supramolecular Atropine Potentiometric Sensor.  |  Ferreira, C., et al. 2021. Sensors (Basel). 21: PMID: 34502770
  11. Uranyl ion complexes with cucurbit [n] urils (n= 6, 7, and 8): A new family of uranyl-organic frameworks.  |  Thuéry, P. 2008. Crystal Growth and Design. 8(11): 4132-4143.
  12. Use of cucurbit [6] uril as ionophore in ion selective electrodes for etilefrine determination in pharmaceuticals  |  Gomes Amorim, C., Araújo, A., & da Conceição Montenegro, M. 2019. Electroanalysis. 31(11): 2171-2178.
  13. Determination of biogenic amines in tomato by ion-pair chromatography coupled to an amine-selective potentiometric detector  |  Gil, R. L., Amorim, C. G., Montenegro, M. C., & Araújo, A. N. 2021. Electrochimica Acta. 378: 138134.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cucurbit[6]uril hydrate, 1 g

sc-252642
1 g
$158.00