CTR1 (h): 293 Lysate: sc-113094

CTR1 (h): 293 Lysate is derived from the 293 cell line, a human embryonic kidney cell line known for its robust growth and high transfection efficiency. This lysate is specifically enriched with human Copper Transporter 1 (CTR1), a high-affinity copper uptake protein that plays a crucial role in maintaining cellular copper homeostasis. CTR1 is a transmembrane protein that facilitates the entry of copper ions into cells, which are essential for various biological processes, including mitochondrial respiration, antioxidant defense, and the functioning of several enzymes. In research, CTR1 (h): 293 Lysate is used to study the mechanisms of copper uptake and regulation within cells. Researchers employ this lysate in Western blotting to detect and quantify CTR1 expression levels under various experimental conditions, providing insights into its regulation by factors such as dietary copper levels and oxidative stress. The lysate is also utilized in co-immunoprecipitation assays to identify protein-protein interactions involving CTR1, helping to explain its role in copper transport and its interaction with other copper-regulating proteins. Functional assays using CTR1 (h): 293 Lysate can assess the impact of CTR1 on cellular copper uptake and distribution, contributing to the understanding of how cells manage copper availability and prevent toxicity. These studies are crucial for unraveling the molecular mechanisms by which CTR1 influences copper homeostasis and its broader implications in cellular metabolism and physiology.