CruzQuench™ 2WS succinimidyl ester (CQ2WS) is designed to be a superior quencher to FAM, HEX, TET, JOE, CFLsm2 and rhodamine 6G. CQ2WS has (a). much stronger absorption; (b). much higher quenching efficiency; and (c). versatile reactive forms with much greater water solubility than other existing quenchers for labeling oligonucleotides and peptides. This CQ2WS product is the most-water soluble and non-fluorescent quencher for labeling oligos and peptides. We have demonstrated that CQ2WS is extremely useful for enhancing the water solubility of hydrophobic peptides. CQ2WS, SE readily reacts with aliphatic amines including amino acids, peptides, amino-modified oligos and proteins.
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