Date published: 2025-10-19

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Creosote (CAS 8021-39-4)

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Application:
Creosote is a biochemical from beechwood tar often used as a preservative and antiseptic
CAS Number:
8021-39-4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Creosote, a complex chemical mixture found from the result of coal tar distillation, serves as a wood preservative, safeguarding against decay and insect damage. Its application in this capacity spans over a hundred years. The substance′s safety profile has been the focus of extensive research, including health effects as a result of exposure to creosote. While the precise biological interactions are not entirely clear, the compounds in creosote are thought to interfere with cellular functions and DNA integrity, which could potentially lead to mutations.


Creosote (CAS 8021-39-4) References

  1. Creosote toxicity to photosynthesis and plant growth in aquatic microcosms.  |  Marwood, CA., et al. 2003. Environ Toxicol Chem. 22: 1075-85. PMID: 12729217
  2. Bioremediation of creosote-contaminated soil in South Africa by landfarming.  |  Atagana, HI. 2004. J Appl Microbiol. 96: 510-20. PMID: 14962131
  3. Wood creosote inhibits calcium mobilization in Guinea pig colonic smooth muscle.  |  Morino, H., et al. 2004. Biol Pharm Bull. 27: 1046-51. PMID: 15256738
  4. Wood creosote prevents CRF-induced motility via 5-HT3 receptors in proximal and 5-HT4 receptors in distal colon in rats.  |  Ataka, K., et al. 2007. Auton Neurosci. 133: 136-45. PMID: 17182287
  5. Creosote released from railway-ties recycled and the sanitary risks.  |  Zicari, G., et al. 2013. Ig Sanita Pubbl. 69: 209-28. PMID: 23743701
  6. Efficacious rat model displays non-toxic effect with Korean beechwood creosote: a possible antibiotic substitute.  |  Quynh, AN., et al. 2014. Biotechnol Biotechnol Equip. 28: 447-454. PMID: 26019530
  7. Creosote Bush (Larrea tridentata) Improves Insulin Sensitivity and Reduces Plasma and Hepatic Lipids in Hamsters Fed a High Fat and Cholesterol Diet.  |  Del Vecchyo-Tenorio, G., et al. 2016. Front Pharmacol. 7: 194. PMID: 27445827
  8. Comprehensive composition of Creosote using comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry (GCxGC-TOFMS).  |  Gallacher, C., et al. 2017. Chemosphere. 178: 34-41. PMID: 28315805
  9. Inhibition of Acetylcholinesterase by Wood Creosote and Simple Phenolic Compounds.  |  Ogata, N., et al. 2020. Chem Pharm Bull (Tokyo). 68: 1193-1200. PMID: 33268651
  10. Biodegradation of creosote-treated wood by two novel constructed microbial consortia for the enhancement of methane production.  |  Ali, SS., et al. 2021. Bioresour Technol. 323: 124544. PMID: 33360721
  11. Wood‑feeding termites as an obscure yet promising source of bacteria for biodegradation and detoxification of creosote-treated wood along with methane production enhancement.  |  Ali, SS., et al. 2021. Bioresour Technol. 338: 125521. PMID: 34273631
  12. The Inhibitory Effect of Wood Creosote on the Movement of Anisakis Larvae: An Implication for the Treatment of Acute Anisakiasis.  |  Ogata, N. and Tagishi, H. 2021. Pharmacology. 106: 637-643. PMID: 34537769
  13. PUF-Immobilized Bjerkandera adusta DSM 3375 as a Tool for Bioremediation of Creosote Oil Contaminated Soil.  |  Struszczyk-Świta, K., et al. 2022. Int J Mol Sci. 23: PMID: 36293297
  14. Magnetic signatures of a creosote oil contaminated site: case study in São Paulo, Brazil.  |  de Moraes, CS., et al. 2022. Sci Rep. 12: 21853. PMID: 36528719
  15. Pyrolysis and Torrefaction-Thermal Treatment of Creosote-Impregnated Railroad Ties as a Method of Utilization.  |  Kazimierski, P., et al. 2023. Materials (Basel). 16: PMID: 37048999

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Creosote, 250 ml

sc-362180
250 ml
$178.00

Creosote, 1 L

sc-362180A
1 L
$565.00