Date published: 2026-2-1

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CREBtide (CAS 149155-45-3)

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Alternate Names:
KRREILSRRPSYR
Application:
CREBtide is a synthetic substrate for PKA and PKC
CAS Number:
149155-45-3
Purity:
≥97% by HPLC
Molecular Weight:
1717
Molecular Formula:
C73H129N29O19
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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CREBtide is a synthetic substrate for PKA. The sequence is derived from phosphorylation sequence in δ-CREB; also reactive with additional species, including cow and dog.


CREBtide (CAS 149155-45-3) References

  1. cAMP-dependent protein kinase, but not the cGMP-dependent enzyme, rapidly phosphorylates delta-CREB, and a synthetic delta-CREB peptide.  |  Colbran, JL., et al. 1992. Biochem Cell Biol. 70: 1277-82. PMID: 1338414
  2. A microPLC-based approach for determining kinase-substrate specificity.  |  Wu, J., et al. 2007. Assay Drug Dev Technol. 5: 559-66. PMID: 17767424
  3. FgSnt1 of the Set3 HDAC complex plays a key role in mediating the regulation of histone acetylation by the cAMP-PKA pathway in Fusarium graminearum.  |  Gong, C., et al. 2022. PLoS Genet. 18: e1010510. PMID: 36477146
  4. Use of a synthetic peptide as a selective substrate for glycogen synthase kinase 3.  |  Wang, QM., et al. 1994. Anal Biochem. 220: 397-402. PMID: 7978284

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

CREBtide, 1 mg

sc-3102
1 mg
$97.00