Date published: 2026-4-24

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Creatinine-d3 (CAS 143827-20-7)

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Alternate Names:
Creatinine-d3 also known as 2-Amino-1,5-dihydro-1-(methyl-d3)-4H-imidazol-4-one; 1-(Methyl-d3)glycocyamidine; 1-(Methyl-d3)hydantoin-2-imide; 2-Amino-1-(methyl-d3)-1,5-dihydroimidazol-4-one; 2-Amino-1-(methyl-d3)imidazolin-4-one; NSC 13123-d3; TEGO Cosmo C 250-d3
Application:
Creatinine-d3 is a deuterium labeled end product of creatine catabolism and can be used for quantification
CAS Number:
143827-20-7
Purity:
98% Isotopic Purity 99%
Molecular Weight:
116.14
Molecular Formula:
C4H4D3N3O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Creatinine-d3 is the labeled form of Creatinine, the end product of creatine catabolism. Creatinine-d3 contains three deuterium atoms. Creatinine-d3 is also found with creatine in muscle tissues and blood. Creatinine-d3 can be used for quantification of creatinine by GC- or LC- mass spectrometry.


Creatinine-d3 (CAS 143827-20-7) References

  1. Development of a liquid chromatography-mass spectrometry method for the high-accuracy determination of creatinine in serum.  |  Stokes, P. and O'Connor, G. 2003. J Chromatogr B Analyt Technol Biomed Life Sci. 794: 125-36. PMID: 12888205
  2. Analysis of creatine, creatinine, creatine-d3 and creatinine-d3 in urine, plasma, and red blood cells by HPLC and GC-MS to follow the fate of ingested creatine-d3.  |  MacNeil, L., et al. 2005. J Chromatogr B Analyt Technol Biomed Life Sci. 827: 210-5. PMID: 16182618
  3. Validation of a liquid chromatography tandem mass spectrometry assay for serum creatinine and comparison with enzymatic and Jaffe methods.  |  Owen, LJ., et al. 2006. Ann Clin Biochem. 43: 118-23. PMID: 16536913
  4. LC-MS-MS Measurements of Urinary Creatinine and the Application of Creatinine Normalization Technique on Cotinine in Smokers' 24 Hour Urine.  |  Hou, H., et al. 2012. J Anal Methods Chem. 2012: 245415. PMID: 23209947
  5. A clinical biomarker assay for the quantification of d3-creatinine and creatinine using LC-MS/MS.  |  Leonard, M., et al. 2014. Bioanalysis. 6: 745-59. PMID: 24702109
  6. Determination of Urinary Creatinine in Washington State Residents via Liquid Chromatography/Tandem Mass Spectrometry.  |  West, CE. and Rhodes, BN. 2014. Int J Anal Chem. 2014: 247316. PMID: 25614740
  7. Development and validation of an ultra-high performance liquid chromatography-tandem mass spectrometry method to measure creatinine in human urine.  |  Fraselle, S., et al. 2015. J Chromatogr B Analyt Technol Biomed Life Sci. 988: 88-97. PMID: 25756209
  8. Organ distribution of endogenous p-cresol in hemodialysis patients.  |  Ikematsu, N., et al. 2019. J Med Invest. 66: 81-85. PMID: 31064961
  9. Value of Plasma NGAL and Creatinine on First Day of Admission in the Diagnosis of Cardiorenal Syndrome Type 1.  |  Phan Thai, H., et al. 2020. Cardiol Res Pract. 2020: 2789410. PMID: 33083054
  10. Application of multi-parameter population model based on endogenous population biomarkers and flow volume in wastewater epidemiology.  |  Hou, C., et al. 2021. Sci Total Environ. 759: 143480. PMID: 33213920
  11. A simplified, rapid LC-MS/MS assay for serum and salivary creatinine.  |  Bernstone, L., et al. 2019. Clin Mass Spectrom. 11: 21-26. PMID: 34841069
  12. Assessment of creatinine concentration in whole blood spheroids using paper spray ionization-tandem mass spectrometry.  |  Sham, TT., et al. 2022. Sci Rep. 12: 14308. PMID: 35995992
  13. Quantification of Gut Microbiota Dysbiosis-Related Organic Acids in Human Urine Using LC-MS/MS.  |  Lee, YT., et al. 2022. Molecules. 27: PMID: 36080134

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Creatinine-d3, 2.5 mg

sc-217956
2.5 mg
$262.00