Date published: 2025-10-15

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Creatinine, anhydrous (CAS 60-27-5)

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Alternate Names:
2-Amino-1-methyl-2-imidazolin-4-one, 2-Imino-1-methylimidazolidin-4-one, 2-Imino-N-methylhydantoin
Application:
Creatinine, anhydrous is a substrate for creatininase
CAS Number:
60-27-5
Purity:
≥98%
Molecular Weight:
113.12
Molecular Formula:
C4H7N3O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Creatinine, anhydrous is a compound that serves as an important indicator of renal function in research. It is produced from creatine and creatine phosphate through a non-enzymatic conversion process that occurs in muscle tissue. In research applications, creatinine, anhydrous is used as a standard or reference compound in assays that measure creatinine levels in biological fluids, which reflect glomerular filtration rate in the kidneys. Studies involving creatinine, anhydrous aim to refine the methods of assessing kidney function and to explore the kinetics of creatinine production and clearance in the body. The compound is also used in investigations related to changes in muscle metabolism under various physiological and pathological conditions, as muscle mass and activity can influence creatinine levels.


Creatinine, anhydrous (CAS 60-27-5) References

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  2. Dietary interrelationships among arginine, methionine, and lysine in young broiler chicks.  |  Chamruspollert, M., et al. 2002. Br J Nutr. 88: 655-60. PMID: 12493087
  3. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate.  |  Levey, AS., et al. 2006. Ann Intern Med. 145: 247-54. PMID: 16908915
  4. Disposition of plasma creatinine in non-azotaemic and moderately azotaemic cats.  |  Le Garreres, A., et al. 2007. J Feline Med Surg. 9: 89-96. PMID: 17049290
  5. Utility of serum cystatin C as a clinical measure of renal function in dogs.  |  Wehner, A., et al. 2008. J Am Anim Hosp Assoc. 44: 131-8. PMID: 18451071
  6. Sulfur-adlayer-coated gold electrode for the in vitro electrochemical detection of uric acid in urine.  |  Miah, MR., et al. 2010. Anal Chim Acta. 669: 75-80. PMID: 20510906
  7. Creatine metabolism and psychiatric disorders: Does creatine supplementation have therapeutic value?  |  Allen, PJ. 2012. Neurosci Biobehav Rev. 36: 1442-62. PMID: 22465051
  8. A new and fast methodology to assess oxidative damage in cardiovascular diseases risk development through eVol-MEPS-UHPLC analysis of four urinary biomarkers.  |  Mendes, B., et al. 2013. Talanta. 116: 164-72. PMID: 24148388
  9. Tandem measurements of iron and creatinine by cross injection analysis with application to urine from thalassemic patients.  |  Choengchan, N., et al. 2015. Talanta. 133: 52-8. PMID: 25435226
  10. Development and validation of an ultra-high performance liquid chromatography-tandem mass spectrometry method to measure creatinine in human urine.  |  Fraselle, S., et al. 2015. J Chromatogr B Analyt Technol Biomed Life Sci. 988: 88-97. PMID: 25756209
  11. Ficolin B in Diabetic Kidney Disease in a Mouse Model of Type 1 Diabetes.  |  Holt, CB., et al. 2015. Mediators Inflamm. 2015: 653260. PMID: 26339138
  12. Glyoxal and methylglyoxal determination in urine by surfactant-assisted dispersive liquid-liquid microextraction and LC.  |  Campillo, N., et al. 2017. Bioanalysis. 9: 369-379. PMID: 28102703
  13. Creasensor: SIMPLE technology for creatinine detection in plasma.  |  Dal Dosso, F., et al. 2018. Anal Chim Acta. 1000: 191-198. PMID: 29289308
  14. Simultaneous and direct determination of urea and creatinine in human urine using a cost-effective flow injection system equipped with in-house contactless conductivity detector and LED colorimeter.  |  Chaneam, S., et al. 2019. Anal Chim Acta. 1073: 54-61. PMID: 31146836
  15. Stir bar sorptive-dispersive microextraction by a poly(methacrylic acid-co-ethylene glycol dimethacrylate)-based magnetic sorbent for the determination of tricyclic antidepressants and their main active metabolites in human urine.  |  Vállez-Gomis, V., et al. 2022. Mikrochim Acta. 189: 52. PMID: 35000010
  16. Innovated single flush on-line solid-phase extraction in bead injection format for flow programming-based determination of creatinine in human urine.  |  Chocholouš, P., et al. 2023. Talanta. 258: 124420. PMID: 36907165

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Creatinine, anhydrous, 10 mg

sc-207458
10 mg
$32.00

Creatinine, anhydrous, 10 g

sc-207458A
10 g
$38.00

Creatinine, anhydrous, 100 g

sc-207458B
100 g
$214.00

Creatinine, anhydrous, 250 g

sc-207458C
250 g
$502.00