Date published: 2025-12-13

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Creatine monohydrate (CAS 6020-87-7)

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Alternate Names:
N-Amidinosarcosine monohydrate
Application:
Creatine monohydrate is involved with rapid ATP production primarily in skeletal muscle tissue via the action of creatine kinase(s)
CAS Number:
6020-87-7
Molecular Weight:
149.15
Molecular Formula:
C4H9N3O2•H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state.


Creatine monohydrate (CAS 6020-87-7) References

  1. Effects of creatine supplementation and resistance training on muscle strength and weightlifting performance.  |  Rawson, ES. and Volek, JS. 2003. J Strength Cond Res. 17: 822-31. PMID: 14636102
  2. Effects of whey isolate, creatine, and resistance training on muscle hypertrophy.  |  Cribb, PJ., et al. 2007. Med Sci Sports Exerc. 39: 298-307. PMID: 17277594
  3. Creatine supplementation.  |  Hall, M. and Trojian, TH. 2013. Curr Sports Med Rep. 12: 240-4. PMID: 23851411
  4. The effects of pre versus post workout supplementation of creatine monohydrate on body composition and strength.  |  Antonio, J. and Ciccone, V. 2013. J Int Soc Sports Nutr. 10: 36. PMID: 23919405
  5. Creatine and creatine forms intended for sports nutrition.  |  Andres, S., et al. 2017. Mol Nutr Food Res. 61: PMID: 28019093
  6. Dietary Supplements for Health, Adaptation, and Recovery in Athletes.  |  Rawson, ES., et al. 2018. Int J Sport Nutr Exerc Metab. 28: 188-199. PMID: 29345167
  7. Effect of the Combination of Creatine Monohydrate Plus HMB Supplementation on Sports Performance, Body Composition, Markers of Muscle Damage and Hormone Status: A Systematic Review.  |  Fernández-Landa, J., et al. 2019. Nutrients. 11: PMID: 31635165
  8. Benefits of Creatine Supplementation for Vegetarians Compared to Omnivorous Athletes: A Systematic Review.  |  Kaviani, M., et al. 2020. Int J Environ Res Public Health. 17: PMID: 32349356
  9. Sarcopenia: Etiology, Nutritional Approaches, and miRNAs.  |  Cannataro, R., et al. 2021. Int J Mol Sci. 22: PMID: 34575884
  10. The Paradoxical Effect of Creatine Monohydrate on Muscle Damage Markers: A Systematic Review and Meta-Analysis.  |  Doma, K., et al. 2022. Sports Med. 52: 1623-1645. PMID: 35218552
  11. Bioavailability, Efficacy, Safety, and Regulatory Status of Creatine and Related Compounds: A Critical Review.  |  Kreider, RB., et al. 2022. Nutrients. 14: PMID: 35268011
  12. Creatine supplementation for older adults: Focus on sarcopenia, osteoporosis, frailty and Cachexia.  |  Candow, DG., et al. 2022. Bone. 162: 116467. PMID: 35688360
  13. A randomized open-labeled study to examine the effects of creatine monohydrate and combined training on jump and scoring performance in young basketball players.  |  Vargas-Molina, S., et al. 2022. J Int Soc Sports Nutr. 19: 529-542. PMID: 35966022
  14. Effects of Creatine Monohydrate on Endurance Performance in a Trained Population: A Systematic Review and Meta-analysis.  |  Fernández-Landa, J., et al. 2023. Sports Med. 53: 1017-1027. PMID: 36877404

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Creatine monohydrate, 100 g

sc-257262
100 g
$43.00

Creatine monohydrate, 1 kg

sc-257262A
1 kg
$122.00