creatine kinase-B Antibody (B-9): sc-373686
- creatine kinase-B Antibody (B-9) is a mouse monoclonal IgG3 κ creatine kinase-B antibody, cited in 4 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 3-30 at the N-terminus of creatine kinase-B of human origin
- recommended for detection of creatine kinase-B chain of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgGκ BP-HRP is the preferred secondary detection reagent for creatine kinase-B Antibody (B-9) for WB applications. This reagent is now offered in a bundle with creatine kinase-B Antibody (B-9) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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Creatine kinase-B Antibody (B-9) is a mouse monoclonal IgG3 kappa light chain antibody that detects creatine kinase-B protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-creatine kinase-B antibody (B-9) is available as the non-conjugated form. Creatine kinase-B protein plays a crucial role in cellular energy metabolism, particularly in tissues with high energy demands, such as the brain and muscle. Creatine kinase-B (B-9) antibody catalyzes the reversible transfer of phosphate from ATP to creatine, forming phosphocreatine and ADP, which serves as a rapid energy reservoir during periods of intense activity. This function is vital for maintaining ATP levels and supporting cellular processes that require bursts of energy, such as muscle contraction and neuronal signaling. The regulation of ATP levels by creatine kinases is essential for proper functioning of various cell types, including muscle fibers, neurons, and other tissues, ensuring that energy supply meets fluctuating demands of cellular activities. Anti-creatine kinase-B antibody (B-9) enables researchers to gain insights into the role of this important enzyme in energy metabolism and its implications in various physiological and pathological conditions.
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creatine kinase-B Antibody (B-9) References:
- Complete nucleotide sequence of the human creatine kinase B gene. | Mariman, EC., et al. 1989. Nucleic Acids Res. 17: 6385. PMID: 2771648
- Isolation and characterization of the gene and cDNA encoding human mitochondrial creatine kinase. | Haas, RC., et al. 1989. J Biol Chem. 264: 2890-7. PMID: 2914937
- cDNA cloning and mapping of the human creatine kinase M gene to 19q13. | Nigro, JM., et al. 1987. Am J Hum Genet. 40: 115-25. PMID: 3031982
- Structure and expression of the human creatine kinase B gene. | Mariman, EC., et al. 1987. Genomics. 1: 126-37. PMID: 3692484
- Creatine kinase in non-muscle tissues and cells. | Wallimann, T. and Hemmer, W. 1994. Mol Cell Biochem. 133-134: 193-220. PMID: 7808454
- Some new aspects of creatine kinase (CK): compartmentation, structure, function and regulation for cellular and mitochondrial bioenergetics and physiology. | Wallimann, T., et al. 1998. Biofactors. 8: 229-34. PMID: 9914824
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
creatine kinase-B Antibody (B-9) | sc-373686 | 200 µg/ml | $316.00 | |||
creatine kinase-B Antibody (B-9): m-IgGκ BP-HRP Bundle | sc-552016 | 200 µg Ab; 40 µg BP | $354.00 | |||
creatine kinase-B (B-9) Neutralizing Peptide | sc-373686 P | 100 µg/0.5 ml | $68.00 |