Molecular structure of CP 80633, CAS Number: 135637-46-6
CP 80633 (CAS 135637-46-6)
Alternate Names:
5-[3-[(1S,2S,4R)-Bicyclo[2.2.1]hept-2-yloxy]-4-methoxyphenyl]tetrahydro-2(1H)-pyrimidinone
Application:
CP 80633 is a selective inhibitor of phosphodiesterase type 4
CAS Number:
135637-46-6
Molecular Weight:
316.39
Molecular Formula:
C18H24N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Selective inhibitor of phosphodiesterase type 4 which does not display significant isozyme selectivity of PDE4. Inhibits hydrolysis of cAMP in isolated monocytes, eosinophils, human peripheral blood and T cells. Exhibits anti-inflammatory and bronchodilatory activity in vivo.
CP 80633 (CAS 135637-46-6) References
Turner et al (1996) The in vivo pharmacology of CP-80,633, a selective inhibitor of phosphodiesterase 4. J.Pharmacol.Exp.Ther. 278 1349. Cohan et al (1996) In vitro pharmacology of the novel phosphodiesterase type 4 inhibitor, CP-80633. J.Pharmacol.Exp.Ther. 278 1356. Cheng et al (1997) The phosphodiesterase type 4 (PDE4) inhibitor CP-80,633 elevates plasma cyclic AMP levels and decreases tumor necrosis factor-a (TNFa) production in mice: effect of adrenalectomy. J.Pharmacol.Exp.Ther. 280 621.Inhibitor of:
PDE.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CP 80633, 10 mg | sc-205276 | 10 mg | $205.00 | |||
CP 80633, 50 mg | sc-205276A | 50 mg | $810.00 |