Molecular structure of CP 135807, CAS Number: 151272-90-1
CP 135807 (CAS 151272-90-1)
Application:
CP 135807 is a selective receptor agonist of SR-1D
CAS Number:
151272-90-1
Molecular Weight:
351.4
Molecular Formula:
C19H21N5O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
Safety Information
SDS & Certificate of Analysis
CP 135807 is a selective receptor agonist of 5-HT1D. This compound has been shown to dose-dependently lower the extracellular 5-HT concentration.
CP 135807 (CAS 151272-90-1) References
- The antipsychotic drug risperidone interacts with auto- and hetero-receptors regulating serotonin output in the rat frontal cortex. | Hertel, P., et al. 1999. Neuropharmacology. 38: 1175-84. PMID: 10462130
- Receptor-mediated regulation of serotonin output in the rat dorsal raphe nucleus: effects of risperidone. | Hertel, P., et al. 2001. Psychopharmacology (Berl). 153: 307-14. PMID: 11271402
- Failure to detect in vivo inverse agonism of the 5-HT(1B) receptor antagonist SB-224289 in 5-HT-depleted guinea-pigs. | Stenfors, C. and Ross, SB. 2002. Naunyn Schmiedebergs Arch Pharmacol. 365: 462-7. PMID: 12070760
- Pharmacology of a novel selective 5-hydroxytryptamine1B receptor antagonist, AR-A000002. | Stenfors, C., et al. 2004. Naunyn Schmiedebergs Arch Pharmacol. 369: 330-7. PMID: 14758468
- Targeting protein-protein interactions for therapeutic discovery via FRET-based high-throughput screening in living cells. | Stroik, DR., et al. 2018. Sci Rep. 8: 12560. PMID: 30135432
- Stimulating DDX3 expression by serotonin 5-HT receptor 7 through phosphorylation of p53 via the AC-PKA-ERK signaling pathway. | Kang, LJ., et al. 2019. J Cell Biochem. 120: 18193-18208. PMID: 31172579
- Serotonergic drugs modulate the phase behavior of complex lipid bilayers. | Musabirova, G., et al. 2022. Biochimie. 203: 40-50. PMID: 35447219
- Combined administration of a 5-hydroxytryptamine (5-HT)1D antagonist and a 5-HT reuptake inhibitor synergistically increases 5-HT release in guinea pig hypothalamus in vivo. | Rollema, H., et al. 1996. J Neurochem. 67: 2204-7. PMID: 8863532
- CP-135,807, a selective 5-HT1D agonist: effects in drug discrimination and punishment procedures in the pigeon. | Mansbach, RS., et al. 1996. Psychopharmacology (Berl). 128: 313-9. PMID: 8972551
- Do 5-HT1B/1D autoreceptors modulate dorsal raphe cell firing? In vivo electrophysiological studies in guinea pigs with GR127935. | Sprouse, J., et al. 1997. Neuropharmacology. 36: 559-67. PMID: 9225281
Inhibitor of:
α1D-AR.Activator of:
SR-1D.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CP 135807, 10 mg | sc-361155 | 10 mg | $169.00 | |||
CP 135807, 50 mg | sc-361155A | 50 mg | $681.00 |