Date published: 2025-12-26

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Coumarin 7 (CAS 27425-55-4)

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Alternate Names:
3-(2-Benzimidazolyl)-7-(diethylamino)coumarin
CAS Number:
27425-55-4
Molecular Weight:
333.38
Molecular Formula:
C20H19N3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Coumarin 7 is a fluorescent dye that is used as a tracer in various experimental applications. It functions by binding to specific molecules or structures within cells, allowing to visualize and track their movement and localization. This dye has a high affinity for certain cellular components, which may be useful for studying cellular processes such as endocytosis, exocytosis, and membrane dynamics. Coumarin 7 emits a strong fluorescent signal when excited by specific wavelengths of light, enabling to observe and analyze the behavior of the labeled molecules in real time. Its mechanism of action involves intercalating into the lipid bilayer of cellular membranes, where it can interact with lipids and proteins, influencing their behavior and function. This property makes Coumarin 7 useful for investigating membrane-related processes and studying the dynamics of cellular organelles., Coumarin 7 plays a significant role in enabling the visualization and analysis of cellular structures and processes in various experimental.


Coumarin 7 (CAS 27425-55-4) References

  1. Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism.  |  Shah, MB., et al. 2016. Mol Pharmacol. 89: 435-45. PMID: 26826176
  2. Cancer Hazard Identification Integrating Human Variability: The Case of Coumarin.  |  Hsieh, CJ., et al. 2019. Int J Toxicol. 38: 501-552. PMID: 31845612
  3. Exploration of Self-Aggregation of Coumarin 7 and Coumarin 30 in Water: Role of β-Cyclodextrin as a Modulator.  |  Das, A., et al. 2021. J Phys Chem B. 125: 13482-13493. PMID: 34865492
  4. Highly Diluted Glyphosate Mitigates Its Effects on Artemia salina: Physicochemical Implications.  |  Nagai, MYDO., et al. 2023. Int J Mol Sci. 24: PMID: 37298430
  5. Variability of coumarin 7- and 3-hydroxylation in a Jordanian population is suggestive of a functional polymorphism in cytochrome P450 CYP2A6.  |  Hadidi, H., et al. 1998. Eur J Clin Pharmacol. 54: 437-41. PMID: 9754990

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Coumarin 7, 100 mg

sc-252640
100 mg
$49.00