Date published: 2026-3-6

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Corydaline (CAS 518-69-4)

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Application:
Corydaline is an alkaloid derivative of corydalis
CAS Number:
518-69-4
Molecular Weight:
369.45
Molecular Formula:
C22H27NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Corydaline is an alkaloid derivative of corydalis. Corydaline, an alkaloid naturally found in the Corydalis species of flowering plants. Currently, extensive scientific studies are being conducted to explore its potential applications. Research on corydaline has been conducted both in vivo and in vitro.


Corydaline (CAS 518-69-4) References

  1. Rapid TLC/GC-MS identification of acetylcholinesterase inhibitors in alkaloid extracts.  |  Berkov, S., et al. 2008. Phytochem Anal. 19: 411-9. PMID: 18446766
  2. Acetylcholinesterase inhibitors from Corydalis yanhusuo.  |  Xiao, HT., et al. 2011. Nat Prod Res. 25: 1418-22. PMID: 20234973
  3. Effects of corydaline from Corydalis tuber on gastric motor function in an animal model.  |  Lee, TH., et al. 2010. Biol Pharm Bull. 33: 958-62. PMID: 20522959
  4. Corydaline inhibits multiple cytochrome P450 and UDP-glucuronosyltransferase enzyme activities in human liver microsomes.  |  Ji, HY., et al. 2011. Molecules. 16: 6591-602. PMID: 21826053
  5. Preclinical pharmacokinetics, tissue distribution and excretion studies of a potential analgesics - corydaline using an ultra performance liquid chromatography-tandem mass spectrometry.  |  Wang, J., et al. 2013. J Chromatogr B Analyt Technol Biomed Life Sci. 942-943: 70-6. PMID: 24216274
  6. Pharmacokinetics of chlorogenic acid and corydaline in DA-9701, a new botanical gastroprokinetic agent, in rats.  |  Jung, JW., et al. 2014. Xenobiotica. 44: 635-43. PMID: 24417753
  7. Gender differences in corydaline pharmacokinetics in rats.  |  Jung, JW., et al. 2015. Xenobiotica. 45: 456-63. PMID: 25430796
  8. Corydaline inhibits enterovirus 71 replication by regulating COX-2 expression.  |  Wang, HQ., et al. 2017. J Asian Nat Prod Res. 19: 1124-1133. PMID: 29034730
  9. Metabolic profiles of corydaline in rats by ultra-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry.  |  Chai, L., et al. 2019. Xenobiotica. 49: 80-89. PMID: 29235899
  10. The comparative pharmacokinetic study of Yuanhu Zhitong prescription based on five quality-markers.  |  Zhang, H., et al. 2018. Phytomedicine. 44: 148-154. PMID: 29523382
  11. Identification of quality markers of Yuanhu Zhitong tablets based on integrative pharmacology and data mining.  |  Li, K., et al. 2018. Phytomedicine. 44: 212-219. PMID: 29551644
  12. Corydaline and l-tetrahydropalmatine attenuate morphine-induced conditioned place preference and the changes in dopamine D2 and GluA1 AMPA receptor expression in rats.  |  Jiang, WN., et al. 2020. Eur J Pharmacol. 884: 173397. PMID: 32717192
  13. Identification and characterization of plant-derived alkaloids, corydine and corydaline, as novel mu opioid receptor agonists.  |  Kaserer, T., et al. 2020. Sci Rep. 10: 13804. PMID: 32796875
  14. Interactions of Isoquinoline Alkaloids with Transition Metals Iron and Copper.  |  Parvin, MS., et al. 2022. Molecules. 27: PMID: 36234964

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Corydaline, 100 mg

sc-280648
100 mg
$166.00

Corydaline, 250 mg

sc-280648A
250 mg
$315.00