Molecular structure of Corticosterone, CAS Number: 50-22-6
Corticosterone (CAS 50-22-6)
See product citations (2)
Alternate Names:
Kendall′s compound B; Reichstein′s substance H; Coumpound B
Application:
Corticosterone is an activator of MCRs and GRs
CAS Number:
50-22-6
Molecular Weight:
346.46
Molecular Formula:
C21H30O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Corticosterone is a hormone synthesized in response to stress. It binds and activates MCRs(mineralocorticoid receptors) and GRs (glucocorticoid receptors), which results in altered expression. This eventually affects ionic conductances through the membrane. Corticosterone induces apoptosis in murine bone marrow.
Corticosterone (CAS 50-22-6) References
- Corticosteroids, stress, and aging. | de Kloet, ER. 1992. Ann N Y Acad Sci. 663: 357-71. PMID: 1336332
- Control of neuronal excitability by corticosteroid hormones. | Joëls, M. and de Kloet, ER. 1992. Trends Neurosci. 15: 25-30. PMID: 1374954
- Corticosterone in chicken eggs. | Rettenbacher, S., et al. 2005. Ann N Y Acad Sci. 1046: 193-203. PMID: 16055852
- Measuring corticosterone in feathers: Strengths, limitations, and suggestions for the future. | Romero, LM. and Fairhurst, GD. 2016. Comp Biochem Physiol A Mol Integr Physiol. 202: 112-122. PMID: 27155053
- Corticosterone and timing of migratory departure in a songbird. | Eikenaar, C., et al. 2017. Proc Biol Sci. 284: PMID: 28077768
- Corticosterone Assimilation by a Voluntary Oral Administration in Palatable Food to Rats. | Raya, J., et al. 2019. J Appl Anim Welf Sci. 22: 37-41. PMID: 29749268
- Measurement of corticosterone in mice: a protocol for a mapping review. | Leenaars, CHC., et al. 2020. Lab Anim. 54: 26-32. PMID: 31657274
- Corticosterone's roles in avian migration: Assessment of three hypotheses. | Bauer, CM. and Watts, HE. 2021. Horm Behav. 135: 105033. PMID: 34273707
- Testicular induced corticosterone synthesis in male rats under fasting stress. | Maeda, N., et al. 2022. Steroids. 177: 108947. PMID: 34843801
- Interaction between corticosterone and PER2 in regulating emotional behaviors in the rat. | Ionadi, A. and Johnson, JD. 2022. Psychoneuroendocrinology. 137: 105628. PMID: 34952453
- Effects of corticosterone on BDNF expression and mood behaviours in mice. | Lin, L., et al. 2022. Physiol Behav. 247: 113721. PMID: 35074305
- Corticosterone triggers anti-proliferative and apoptotic effects, and downregulates the ACVR1-SMAD1-ID3 cascade in chicken ovarian prehierarchical, but not preovulatory granulosa cells. | Yang, M., et al. 2022. Mol Cell Endocrinol. 552: 111675. PMID: 35577112
- Chronic elevation of plasma corticosterone causes reductions in the number of cycling cells of the B lineage in murine bone marrow and induces apoptosis. | Garvy, BA., et al. 1993. Immunology. 80: 587-92. PMID: 8307608
Inhibitor of:
β-defensin 119, β-defensin 47, BC014805, Calgranulin C, CGRP1, group III sPLA2, HLA-HB1, LCE2C, OCT, Skint1, Skint5, Skint6, Skint8, Slc22a22, SVCT2, and Telethonin.Activator of:
3β-HSD5, AGP-1, ANKH, Calcyon, GR, LRRC31, MCR, MUP15, Na+/K+-ATPase β2, Neuromedin N, RFRP-2, Slc22a27, SULT2B10, and VGLUT1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Corticosterone, 100 mg | sc-300391 | 100 mg | $57.00 | |||
Corticosterone, 500 mg | sc-300391A | 500 mg | $108.00 |