Coronavirus surface antigen Antibody (5A4): sc-51839

Coronavirus surface antigen Antibody (5A4) is a mouse monoclonal IgG1 antibody that recognizes Coronavirus surface antigen of bovine Coronavirus origin by enzyme-linked immunosorbent assay (ELISA). Anti-Coronavirus surface antigen antibody (5A4) is available in a non-conjugated form, providing researchers with a versatile tool for studying this important viral protein. Coronaviruses, belonging to the family Coronaviridae, are enveloped viruses characterized by their positive-sense single-stranded RNA genome and helical symmetry, which gives them a crown-like appearance under an electron microscope. These viruses primarily target the upper respiratory and gastrointestinal tracts of mammals and birds, with several strains known to infect humans, contributing to common colds and more severe respiratory illnesses. Coronavirus surface antigen (5A4) antibody targets a protein crucial for virus attachment and host cell entry, making this protein a key target for vaccine development and therapeutic interventions. Understanding Coronavirus surface antigen structure and function can inform strategies to inhibit viral entry and replication, ultimately aiding in the control of Coronavirus outbreaks.

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Coronavirus surface antigen Antibody (5A4) References:

1. A review of coronavirus infection in the central nervous system of cats and mice.  |  Foley, JE. and Leutenegger, C. 2001. J Vet Intern Med. 15: 438-44. PMID: 11596730
2. Proteomic analysis on structural proteins of Severe Acute Respiratory Syndrome coronavirus.  |  Ying, W., et al. 2004. Proteomics. 4: 492-504. PMID: 14760722
3. Identification of a novel protein 3a from severe acute respiratory syndrome coronavirus.  |  Yu, CJ., et al. 2004. FEBS Lett. 565: 111-6. PMID: 15135062
4. Detection of human coronavirus NL63 in young children with bronchiolitis.  |  Ebihara, T., et al. 2005. J Med Virol. 75: 463-5. PMID: 15648061
5. Severe acute respiratory syndrome associated coronavirus is detected in intestinal tissues of fatal cases.  |  Shi, X., et al. 2005. Am J Gastroenterol. 100: 169-76. PMID: 15654797
6. Association between a novel human coronavirus and Kawasaki disease.  |  Esper, F., et al. 2005. J Infect Dis. 191: 499-502. PMID: 15655771
7. Receptor-independent infection of murine coronavirus: analysis by spinoculation.  |  Watanabe, R., et al. 2006. J Virol. 80: 4901-8. PMID: 16641281
8. Genetic variability of human coronavirus OC43-, 229E-, and NL63-like strains and their association with lower respiratory tract infections of hospitalized infants and immunocompromised patients.  |  Gerna, G., et al. 2006. J Med Virol. 78: 938-49. PMID: 16721849
9. Entry of coronavirus into primate CNS following peripheral infection.  |  Cabirac, GF., et al. 1994. Microb Pathog. 16: 349-57. PMID: 7815918

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Coronavirus surface antigen Antibody (5A4) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Coronavirus surface antigen Antibody (5A4) Specifications

Alternate Product Name: Coronavirus surface antigen

Product Clone Name: 5A4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Coronavirus surface antigen

Epitope Species: bovine Coronavirus

Product Reactivity/Detection: surface antigen

Species Reactivity/Detection: bovine Coronavirus

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: ELISA

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Coronavirus surface antigen Antibody (5A4): N/A