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COQ7 Antibody (B-12): sc-514029

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Datasheets
  • COQ7 Antibody (B-12) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 152-175 within an internal region of COQ7 of human origin
  • recommended for detection of COQ7 of mouse, rat and human origin by WB, IP, IF and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for COQ7 Antibody (B-12). This work is in progress.
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    COQ7 Antibody (B-12) is a mouse monoclonal IgG2b antibody that detects COQ7 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). COQ7, a homolog of the timing protein CLK-1, is a 217 amino acid protein encoded by the mouse gene Coq7, playing a crucial role in the biosynthesis of Coenzyme Q (CoQ), an essential co-factor in mitochondrial respiration. Anti-COQ7 antibody (B-12) supports research in maintaining mitochondrial integrity and neurogenesis, particularly in tissues with high energy demands such as the heart, muscle, liver, and kidney. After transcription, COQ7 is specifically targeted to the mitochondria, where processing achieves a mature form, highlighting the significance of cellular localization in energy metabolism. The conservation of function among CLK-1, clk-1, and COQ7 gene products suggests a potential link between ubiquinone production and the aging process, making COQ7 a vital protein for understanding mitochondrial health and longevity. COQ7 monoclonal antibody (B-12) serves as an invaluable tool for researchers investigating the intricate roles of this protein in cellular energy dynamics and its implications in age-related diseases.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    COQ7 Antibody (B-12)

    sc-514029
    200 µg/ml
    $322.00

    COQ7 (B-12) Neutralizing Peptide

    sc-514029 P
    100 µg/0.5 ml
    $69.00

    What application is the blocking peptide sc-514029 P appropriate for?

    Asked by: jenniferc
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-28
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    Rated 5 out of 5 by from Great Western blot data of COQ7 expression in THPGreat Western blot data of COQ7 expression in THP-1 and HEK293 whole cell lysates and human heart and mouse heart tissue extracts. -SCBT QC
    Date published: 2013-08-13
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    COQ7 Antibody (B-12) is rated 5.0 out of 5 by 1.
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