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Coproporphyrin III dihydrochloride (CAS 14643-66-4)

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Alternate Names:
Coproporphyrin III dihydrochloride is known as a porphyrin derivative.
Application:
Coproporphyrin III dihydrochloride is a naturally occurring porphyrin derivative, unconnected to symptoms of porphyria.
CAS Number:
14643-66-4
Molecular Weight:
727.63
Molecular Formula:
C36H38N4O82HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Coproporphyrin III dihydrochloride is a naturally occurring porphyrin derivative. Increased Coproporphyrin III dihydrochloride excretion is unlinked by symptoms of porphyria, metal or chemical poisining, or liver disease. Coproporphyrin III dihydrochloride is increased with antioxidants, but uroporphyrin I accumulation suffers as a result.


Coproporphyrin III dihydrochloride (CAS 14643-66-4) References

  1. Effect of insulin and glucagon on accumulation of uroporphyrin and coproporphyrin from 5-aminolevulinate in hepatocyte cultures.  |  Trask, HW., et al. 2005. Arch Biochem Biophys. 439: 1-11. PMID: 15946643
  2. Idiopathic coproporphyrinuria; a hitherto unrecognized form characterized by lack of symptoms in spite of the excretion of large amounts of coproporphyrin.  |  WATSON, CJ. and SCHWARTZ, S. 1949. J Clin Invest. 28: 465-8. PMID: 18127531
  3. Spectrophotometric study of coproporphyrin-I complexes of copper(II) and cobalt(II).  |  Giovannetti, R., et al. 1995. Talanta. 42: 1913-8. PMID: 18966431
  4. Kinetic and equilibrium studies on mercury(II)-coproporphyrin-I. Metal ion exchange reaction with cobalt(II) and application to determination of trace mercury(II).  |  Giovannetti, R. and Bartocci, V. 1998. Talanta. 46: 977-84. PMID: 18967221
  5. Spectrophotometric study of Cd(II), Pb(II), Hg(II) and Zn(II) complexes with 5,10,15,20-tetrakis(4-carboxylphenyl)porphyrin.  |  Kilian, K. and Pyrzyńska, K. 2003. Talanta. 60: 669-78. PMID: 18969091
  6. Reactions of anionic porphyrin with group 11 elements: a spectrophotometric and electrospray ionization mass spectrometry study.  |  Giovannetti, R., et al. 2004. Talanta. 63: 857-64. PMID: 18969510
  7. Is coproporphyrin III a copper-acquisition compound in Paracoccus denitrificans?  |  Anttila, J., et al. 2011. Biochim Biophys Acta. 1807: 311-8. PMID: 21216223
  8. Coproporphyrin III excretion identifies the anaerobic coproporphyrinogen III oxidase HemN as a copper target in the Cu⁺-ATPase mutant copA⁻ of Rubrivivax gelatinosus.  |  Azzouzi, A., et al. 2013. Mol Microbiol. 88: 339-51. PMID: 23448658
  9. A fully automated and validated human plasma LC-MS/MS assay for endogenous OATP biomarkers coproporphyrin-I and coproporphyrin-III.  |  King-Ahmad, A., et al. 2018. Bioanalysis. 10: 691-701. PMID: 29747517
  10. Coproporphyrin III Produced by the Bacterium Glutamicibacter arilaitensis Binds Zinc and Is Upregulated by Fungi in Cheese Rinds.  |  Cleary, JL., et al. 2018. mSystems. 3: PMID: 30175236
  11. Production of copper coproporphyrin III by Bacillus cereus. II. Regulation of the biosynthesis of coproporphyrin III and its copper complex by oxygen and heavy metal ions.  |  Yamada-Ankei, T., et al. 1977. J Biochem. 81: 843-50. PMID: 407222
  12. Isolated Bacillus subtilis HemY has coproporphyrinogen III to coproporphyrin III oxidase activity.  |  Hansson, M., et al. 1997. Biochim Biophys Acta. 1340: 97-104. PMID: 9217019

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Coproporphyrin III dihydrochloride, 10 mg

sc-263072
10 mg
$155.00

Coproporphyrin III dihydrochloride, 100 mg

sc-263072A
100 mg
$1097.00