Copper pyrithione (CAS 154592-20-8)
QUICK LINKS
Copper pyrithione functions as a biocide in experimental applications, inhibiting the growth of various microorganisms. Its mechanism of action involves disrupting the function of enzymes essential for cellular respiration and energy production in target organisms. This disruption leads to the accumulation of toxic byproducts within the cells, ultimately causing cell death. At the molecular level, copper pyrithione interacts with specific metal-binding sites on enzymes, interfering with their ability to catalyze essential biochemical reactions. This interference disrupts the normal functioning of the microorganisms, preventing their growth and proliferation. In experimental applications, copper pyrithione′s mechanism of action may be a useful for studying the mechanisms of microbial resistance and developing strategies to combat microbial contamination in various industrial and environmental applications.
Copper pyrithione (CAS 154592-20-8) References
- Effects of zinc pyrithione and copper pyrithione on microbial community function and structure in sediments. | Groth Petersen, D., et al. 2004. Environ Toxicol Chem. 23: 921-8. PMID: 15095887
- Indirect estimation of degradation time for zinc pyrithione and copper pyrithione in seawater. | Maraldo, K. and Dahllöf, I. 2004. Mar Pollut Bull. 48: 894-901. PMID: 15111036
- Seasonal variations in the effect of zinc pyrithione and copper pyrithione on pelagic phytoplankton communities. | Maraldo, K. and Dahllöf, I. 2004. Aquat Toxicol. 69: 189-98. PMID: 15261454
- Synergistic toxic effects of zinc pyrithione and copper to three marine species: Implications on setting appropriate water quality criteria. | Bao, VW., et al. 2008. Mar Pollut Bull. 57: 616-23. PMID: 18495176
- Toxicity of Diuron and copper pyrithione on the brine shrimp, Artemia franciscana: the effects of temperature and salinity. | Koutsaftis, A. and Aoyama, I. 2008. J Environ Sci Health A Tox Hazard Subst Environ Eng. 43: 1581-5. PMID: 18988093
- Toxicity and metabolism of copper pyrithione and its degradation product, 2,2'-dipyridyldisulfide in a marine polychaete. | Mochida, K., et al. 2011. Chemosphere. 82: 390-7. PMID: 20965543
- The effects of copper pyrithione, an antifouling agent, on developing zebrafish embryos. | Almond, KM. and Trombetta, LD. 2016. Ecotoxicology. 25: 389-98. PMID: 26686506
- Copper pyrithione, a booster biocide, induces abnormal muscle and notochord architecture in zebrafish embryogenesis. | Almond, KM. and Trombetta, LD. 2017. Ecotoxicology. 26: 855-867. PMID: 28573481
- The influence of seawater properties on toxicity of copper pyrithione and its degradation product to brine shrimp Artemia salina. | Lavtizar, V., et al. 2018. Ecotoxicol Environ Saf. 147: 132-138. PMID: 28841528
- Metal-based proteasomal deubiquitinase inhibitors as potential anticancer agents. | Chen, X., et al. 2017. Cancer Metastasis Rev. 36: 655-668. PMID: 29039082
- Acute toxicity test of copper pyrithione on Javanese medaka and the behavioural stress symptoms. | Mohamat-Yusuff, F., et al. 2018. Mar Pollut Bull. 127: 150-153. PMID: 29475647
- Effects of copper pyrithione (CuPT) on apoptosis, ROS production, and gene expression in hemocytes of white shrimp Litopenaeus vannamei. | Chen, T., et al. 2022. Comp Biochem Physiol C Toxicol Pharmacol. 256: 109323. PMID: 35247531
- Water-soluble copper pyrithione complexes with cytotoxic and antibacterial activity. | Mishra, A., et al. 2023. Org Biomol Chem. 21: 2539-2544. PMID: 36877005
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Copper pyrithione, 1 g | sc-357321 | 1 g | $194.00 | |||
Copper pyrithione, 5 g | sc-357321A | 5 g | $597.00 |