Date published: 2025-11-7

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Copper(II) chloride dihydrate (CAS 10125-13-0)

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Alternate Names:
Cupric chloride dihydrate
Application:
Copper(II) chloride dihydrate is able to chlorinate the alpha position of carbonyl compounds
CAS Number:
10125-13-0
Molecular Weight:
170.48
Molecular Formula:
CuCl22H2O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Copper(II) chloride dihydrate may be used in a variety of applications including use as a chlorinating agent; oxidizing agent; Lewis acid; or catalyst for conjugate additions and acylation. Copper(II) chloride is an effective catalyst for the tetrahydropyranylation of alcohols, using mild conditions and in high yields. Used with palladium in a catalytic synthesis of 3-haloindoles via an annulation process. Copper(II) chloride is also used in the synthesis of organic compounds and is able to chlorinate the alpha position of carbonyl compounds.


Copper(II) chloride dihydrate (CAS 10125-13-0) References

  1. Effect of copper(II) chloride on suppression of racemization in peptide synthesis by the carbodiimide method.  |  Miyazawa, T., et al. 1992. Int J Pept Protein Res. 39: 237-44. PMID: 1399263
  2. Reactions of copper(II) chloride in solution: facile formation of tetranuclear copper clusters and other complexes that are relevant in catalytic redox processes.  |  Löw, S., et al. 2013. Chemistry. 19: 5342-51. PMID: 23447462
  3. Gallium-catalyzed reductive chlorination of carboxylic acids with copper(II) chloride.  |  Sakai, N., et al. 2014. J Org Chem. 79: 10619-23. PMID: 25295703
  4. New Dinuclear Macrocyclic Copper(II) Complexes as Potentially Fluorescent and Magnetic Materials.  |  Barwiolek, M., et al. 2023. Int J Mol Sci. 24: PMID: 36769351
  5. Coloration and Fire Retardancy of Transparent Wood Composites by Metal Ions.  |  Samanta, P., et al. 2023. ACS Appl Mater Interfaces. 15: 58850-58860. PMID: 38055951
  6. Safety and efficacy of a feed additive consisting of copper(II)-betaine complex for all animal species (Biochem Zusatzstoffe Handels- und Produktionsges. mbH).  |  , ., et al. 2023. EFSA J. 21: e8460. PMID: 38094106
  7. Enhanced Degradation of Levofloxacin through Visible-Light-Driven Peroxymonosulfate Activation over CuInS2/g-C3N4 Heterojunctions.  |  Zhong, X., et al. 2023. Nanomaterials (Basel). 14: PMID: 38202529
  8. Exploring C-F···π Interactions: Synthesis, Characterization, and Surface Analysis of Copper β-Diketone Complexes.  |  Mirtamizdoust, B., et al. 2024. ACS Omega. 9: 5563-5575. PMID: 38343918
  9. Carbon dots-cadmium sulfide quantum dots nanocomposite for 'on-off' fluorescence sensing of chromium(vi) ions.  |  Patil, AB., et al. 2024. RSC Adv. 14: 12923-12934. PMID: 38650690
  10. Zinc oxide and copper oxide nanoparticles as a potential solution for controlling Phytophthora infestans, the late blight disease of potatoes.  |  AlHarethi, AA., et al. 2024. Discov Nano. 19: 105. PMID: 38907852

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Copper(II) chloride dihydrate, 100 g

sc-211132
100 g
$31.00

Copper(II) chloride dihydrate, 500 g

sc-211132A
500 g
$110.00