Date published: 2026-4-3

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Copper(II) acetate (CAS 142-71-2)

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Alternate Names:
Cupric acetate
Application:
Copper(II) acetate is used in biochemical applications such as DNA extraction
CAS Number:
142-71-2
Molecular Weight:
181.63
Molecular Formula:
C4H6CuO4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Copper(II) acetate is used in biochemical applications such as DNA extraction. Copper(II) complexes have been evaluated for anticancer, antibacterial and antifungal activities. Cu(II) complexes are known to cleave DNA; however, increased efficiency is seen in the presence of an oxidizer (often H2O2). Copper acetate exists in a dimeric structure in the solid state as well as in non-aqueous solution. Has been shown to bind the ribose hydroxyls of both purine and pyrimidine nucleosides. Popular methods for DNA extraction may be hindered by endogenous levels of polysaccharides, phenolics and other organic molecules; Copper(II) acetate treatment has been shown to fix and remove tannins in samples from Pyrus (Pear) yielding high quality DNA.


Copper(II) acetate (CAS 142-71-2) References

  1. Synthesis, antimicrobial activity and chemotherapeutic potential of inorganic derivatives of 2-(4'-thiazolyl)benzimidazole[thiabendazole]: X-ray crystal structures of [Cu(TBZH)2Cl]Cl.H2O.EtOH and TBZH2NO3 (TBZH=thiabendazole).  |  Devereux, M., et al. 2004. J Inorg Biochem. 98: 1023-31. PMID: 15149811
  2. Selective copper(II) acetate and potassium iodide catalyzed oxidation of aminals to dihydroquinazoline and quinazolinone alkaloids.  |  Richers, MT., et al. 2013. Beilstein J Org Chem. 9: 1194-201. PMID: 23843914
  3. Facile 'living' radical polymerization of methyl methacrylate in the presence of iniferter agents: homogeneous and highly efficient catalysis from copper(II) acetate.  |  Jiang, H., et al. 2014. Macromol Rapid Commun. 35: 1332-9. PMID: 24943002
  4. A mild hydration of nitriles catalysed by copper(ii) acetate.  |  Marcé, P., et al. 2016. Chem Commun (Camb). 52: 1436-8. PMID: 26645321
  5. Copper(II) Acetate-Induced Oxidation of Hydrazones to Diazo Compounds under Flow Conditions Followed by Dirhodium-Catalyzed Enantioselective Cyclopropanation Reactions.  |  Wei, B., et al. 2021. Org Lett. 23: 5363-5367. PMID: 34228465
  6. trans-IV restriction: a new configuration for metal bis-cyclam complexes as potent CXCR4 inhibitors.  |  Alzahrani, SO., et al. 2024. Dalton Trans. 53: 5616-5623. PMID: 38439632
  7. Competing Mechanisms in Palladium-Catalyzed Alkoxycarbonylation of Styrene.  |  Mehara, J., et al. 2024. ACS Catal. 14: 5710-5719. PMID: 38660606
  8. SERS detection of dopamine using metal-chelated Ag nanoshell.  |  Kim, M., et al. 2024. RSC Adv. 14: 14214-14220. PMID: 38690106
  9. Electrochemical DNA-nano biosensor for the detection of Goserelin as anticancer drug using modified pencil graphite electrode.  |  Laylani, LAS., et al. 2024. Front Oncol. 14: 1321557. PMID: 38751811
  10. Antibacterial efficacy of copper-based metal-organic frameworks against Escherichia coli and Lactobacillus.  |  Elmehrath, S., et al. 2024. RSC Adv. 14: 15821-15831. PMID: 38752161
  11. A Copper-Selective Sensor and Its Inhibition of Copper-Amyloid Beta Aggregation.  |  Nguyen, NK., et al. 2024. Biosensors (Basel). 14: PMID: 38785721
  12. Recent Advances in Manganese(III)-Assisted Radical Cyclization for the Synthesis of Natural Products: A Comprehensive Review.  |  Biçer, E. and Yılmaz, M. 2024. Molecules. 29: PMID: 38792125
  13. Stereoselective differentiation between ribonucleosides and deoxynucleosides by reaction with the copper(II) acetate dimer.  |  Berger, NA., et al. 1972. Nat New Biol. 239: 237-40. PMID: 4538853

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Copper(II) acetate, 25 g

sc-239581
25 g
$64.00

Copper(II) acetate, 100 g

sc-239581A
100 g
$154.00