connexin 46 Antibody (F-2): sc-377398

connexin 46 Antibody (F-2) is a mouse monoclonal IgG3 kappa light chain antibody that detects connexin 46 of mouse and rat origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-connexin 46 antibody (F-2) is available in a non-conjugated form, specifically designed for researchers studying connexin 46′s role in cellular communication. Connexin 46 is a member of the connexin family, forming hexameric complexes called "connexons" that facilitate low molecular weight molecule transfer between adjacent cells through gap junctions. Connexin 46 maintains lens transparency through intercellular communication within the lens. Disrupted connexin 46 expression can lead to cataracts, highlighting connexin 46′s importance in eye health. Connexin proteins′ structure, featuring four transmembrane α-helical domains and specific extracellular loops, allows channel formation with distinct permeabilities essential for various physiological processes. Connexin 46 exhibits unique properties that other connexins cannot compensate for, making connexin 46 vital for maintaining tissue homeostasis and function.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-connexin 46 Antibody (F-2) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-connexin 46 Antibody (F-2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

connexin 46 Antibody (F-2) Specifications

Alternate Product Name: GJA3

Product Clone Name: F-2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₃ kappa light chain

Amino Acids: 375-411

Epitope Target: connexin 46

Epitope Species: mouse

Product Reactivity/Detection: connexin 46

Species Reactivity/Detection: mouse, rat

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₃ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for connexin 46 Antibody (F-2): P: Blocking Peptide

The preferred connexin 46 antibody is connexin 46 Antibody (C-3): sc-365394.