Date published: 2026-4-3

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Conjugated Linoleic Acid (9Z,11E) (CAS 2540-56-9)

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Alternate Names:
9(Z),11(E)-Conjugated Linoleic Acid; Rumenic Acid; 9Z,11E-CLA; Bovinic acid
Application:
Conjugated Linoleic Acid (9Z,11E) is the predominant isomer of conjugated linoleic acid in animal tissue
CAS Number:
2540-56-9
Molecular Weight:
280.45
Molecular Formula:
C18H32O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Conjugated Linoleic Acid (9Z,11E) is a compound that is extensively studied in the field of food science and nutrition due to its presence in dairy and meat products from ruminants. Its configuration, consisting of conjugated double bonds, is the subject of research focusing on its impact on food quality and stability. Studies on Conjugated Linoleic Acid (9Z,11E) also delve into its role in the modulation of lipid metabolism, where it is thought to influence the composition of fatty acids in cell membranes. This compound is equally of interest in the area of lipid oxidation, as the conjugated double bonds may affect the susceptibility of lipids to oxidative processes, which has implications for both the shelf-life of food products and the nutritional value.


Conjugated Linoleic Acid (9Z,11E) (CAS 2540-56-9) References

  1. The anticarcinogenic conjugated fatty acid c9, t11-c18:2, or rumenic acid, in human milk: amounts and effects.  |  Jensen, RG. and Lammi-Keefe, C. 2001. Adv Exp Med Biol. 501: 153-6. PMID: 11787677
  2. The position of rumenic acid on triacylglycerols alters its bioavailability in rats.  |  Chardigny, JM., et al. 2003. J Nutr. 133: 4212-4. PMID: 14652374
  3. Inhibitory effect of conjugated dienoic derivatives of linoleic acid and beta-carotene on the in vitro growth of human cancer cells.  |  Shultz, TD., et al. 1992. Cancer Lett. 63: 125-33. PMID: 1562989
  4. In vitro metabolism of rumenic acid in bovine liver slices.  |  De La Torre, A., et al. 2005. Reprod Nutr Dev. 45: 441-51. PMID: 16045892
  5. Rumenic acid significantly reduces plasma levels of LDL and small dense LDL cholesterol in hamsters fed a cholesterol- and lipid-enriched semi-purified diet.  |  LeDoux, M., et al. 2007. Lipids. 42: 135-41. PMID: 17393219
  6. Elaidic, vaccenic, and rumenic acid status during pregnancy: association with maternal plasmatic LC-PUFAs and atopic manifestations in infants.  |  Chisaguano, AM., et al. 2014. Pediatr Res. 76: 470-6. PMID: 25119335
  7. Effects of rumenic acid rich conjugated linoleic acid supplementation on cognitive function and handgrip performance in older men and women.  |  Jenkins, NDM., et al. 2016. Exp Gerontol. 84: 1-11. PMID: 27521997
  8. Physicochemical, thermal and computational study of the encapsulation of rumenic acid by natural and modified cyclodextrins.  |  Matencio, A., et al. 2017. Food Chem. 216: 289-95. PMID: 27596422
  9. Protective effect of Rumenic acid rich cow's milk against colitis is associated with the activation of Nrf2 pathway in a murine model.  |  Bergamo, P., et al. 2017. Prostaglandins Leukot Essent Fatty Acids. 125: 14-23. PMID: 28987717
  10. The effect of pomegranate seed oil and grapeseed oil on cis-9, trans-11 CLA (rumenic acid), n-3 and n-6 fatty acids deposition in selected tissues of chickens.  |  Białek, A., et al. 2018. J Anim Physiol Anim Nutr (Berl). 102: 962-976. PMID: 29682807
  11. In silico characterization of linoleic acid biotransformation to rumenic acid in food derived Lactobacillus plantarum YW11.  |  Aziz, T., et al. 2020. Acta Biochim Pol. 67: 99-109. PMID: 32031769
  12. Allosteric modulation of cardiac myosin mechanics and kinetics by the conjugated omega-7,9 trans-fat rumenic acid.  |  Pertici, I., et al. 2021. J Physiol. 599: 3639-3661. PMID: 33942907
  13. When fat meets the engine: implications of dietary rumenic acid on myosin-targeting therapies in heart failure.  |  Sequeira, V. 2021. J Physiol. 599: 3635-3636. PMID: 34114231
  14. Dietary conjugated linoleic acid normalizes impaired glucose tolerance in the Zucker diabetic fatty fa/fa rat.  |  Houseknecht, KL., et al. 1998. Biochem Biophys Res Commun. 244: 678-82. PMID: 9535724
  15. Rumenic acid: a proposed common name for the major conjugated linoleic acid isomer found in natural products.  |  Kramer, JK., et al. 1998. Lipids. 33: 835. PMID: 9727617

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Conjugated Linoleic Acid (9Z,11E), 10 mg

sc-205264
10 mg
$149.00

Conjugated Linoleic Acid (9Z,11E), 50 mg

sc-205264A
50 mg
$577.00

Conjugated Linoleic Acid (9Z,11E), 100 mg

sc-205264B
100 mg
$1007.00

Conjugated Linoleic Acid (9Z,11E), 1 g

sc-205264C
1 g
$3751.00

Conjugated Linoleic Acid (9Z,11E), 10 g

sc-205264D
10 g
$27056.00